SCOP 1.75: Family c.77.1.5: Phosphotransacetylase

Lineage for Family c.77.1.5: Phosphotransacetylase

1. Root: SCOP 1.75

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
   consists of two intertwined (sub)domains related by pseudo dyad; duplication
   3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest

4. Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (5 families)
   the constituent families form similar dimers

5. Family c.77.1.5: Phosphotransacetylase [102663] (2 proteins)
   Pfam PF01515; contains extra beta-alpha unit between strands 2 and 3; closer relationships to the PdxA-like and PlsX-like families

Proteins:

1. Ethanolamine utilization protein EutD [117727] (1 species)

   • Species Escherichia coli [TaxId:562] [117728] (1 PDB entry)
     Uniprot P77218 2-323

2. Phosphotransacetylase Pta [110717] (3 species)

   1. Species Bacillus subtilis [TaxId:1423] [117726] (2 PDB entries)
      Uniprot P39646

   2. Species Methanosarcina thermophila [TaxId:2210] [110718] (3 PDB entries)
      Uniprot P38503

   3. Species Streptococcus pyogenes [TaxId:1314] [102665] (1 PDB entry)

More info for Family c.77.1.5: Phosphotransacetylase

Timeline for Family c.77.1.5: Phosphotransacetylase:

• Family c.77.1.5: Phosphotransacetylase first appeared in SCOP 1.67
  
• Family c.77.1.5: Phosphotransacetylase appears in SCOP 1.73
  
• Family c.77.1.5: Phosphotransacetylase appears in SCOPe 2.01
  
• Family c.77.1.5: Phosphotransacetylase appears in the current release, SCOPe 2.08