Lineage for Protein: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA

  1. Root: SCOPe 2.03
  2. 1336837Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1386088Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
    consists of two intertwined (sub)domains related by pseudo dyad; duplication
    3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest
  4. 1386089Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families) (S)
    the constituent families form similar dimers
  5. 1386334Family c.77.1.3: PdxA-like [102656] (2 proteins)
    Pfam PF04166; contains extra beta-alpha unit between strands 2 and 3; closer relationships to the PlsX-like and phosphotransacetylase families
  6. 1386335Protein 4-hydroxythreonine-4-phosphate dehydrogenase PdxA [102657] (2 species)
    pyridoxal phosphate biosynthetic protein

Species:

  1. 1386336Escherichia coli [TaxId:562] [102658] (3 PDB entries)
    1. Domains for 1ps6:
      1. 1386339Domain d1ps6a_: 1ps6 A: [95070]
        complexed with 4tp, zn
      2. 1386340Domain d1ps6b_: 1ps6 B: [95071]
        complexed with 4tp, zn
    2. Domains for 1ps7:
      1. 1386341Domain d1ps7a_: 1ps7 A: [95072]
        complexed with zn
      2. 1386342Domain d1ps7b_: 1ps7 B: [95073]
        complexed with zn
      3. 1386343Domain d1ps7c_: 1ps7 C: [95074]
        complexed with zn
      4. 1386344Domain d1ps7d_: 1ps7 D: [95075]
        complexed with zn
    3. Domains for 1ptm:
      1. 1386337Domain d1ptma_: 1ptm A: [95104]
        complexed with po4, zn
      2. 1386338Domain d1ptmb_: 1ptm B: [95105]
        complexed with po4, zn
  2. 1386345Salmonella typhimurium [TaxId:90371] [102659] (1 PDB entry)

More info for Protein 4-hydroxythreonine-4-phosphate dehydrogenase PdxA from c.77.1.3: PdxA-like

Timeline for Protein 4-hydroxythreonine-4-phosphate dehydrogenase PdxA from c.77.1.3: PdxA-like: