SCOPe 2.04: Family c.72.3.1: CoaB-like

Lineage for Family c.72.3.1: CoaB-like

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.72: Ribokinase-like [53612] (3 superfamilies)
   core: 3 layers: a/b/a; mixed beta-sheet of 8 strands, order 21345678, strand 7 is antiparallel to the rest
   potential superfamily: members of this fold have similar functions but different ATP-binding sites

4. Superfamily c.72.3: CoaB-like [102645] (2 families)
   combination of the Rossmann-like and Ribokinase-like topologies; mixed beta-sheet of 8 strands, order 32145678, strand 7 is antiparallel to the rest

5. Family c.72.3.1: CoaB-like [102646] (2 proteins)
   Pfam PF04127

Proteins:

1. Coenzyme A biosynthesis bifunctional protein CoaBC, phosphopantothenoylcysteine synthase domain (CoaB) [117722] (1 species)

   • Species Escherichia coli [TaxId:562] [117723] (4 PDB entries)
     Uniprot P24285 181-404

2. Phosphopantothenoylcysteine synthetase [102647] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [102648] (1 PDB entry)

More info for Family c.72.3.1: CoaB-like

Timeline for Family c.72.3.1: CoaB-like:

• Family c.72.3.1: CoaB-like first appeared in SCOP 1.67, called Family c.72.3.1: Phosphopantothenoylcysteine synthetase
  
• Family c.72.3.1: CoaB-like appears in SCOPe 2.03
  
• Family c.72.3.1: CoaB-like appears in SCOPe 2.05
  
• Family c.72.3.1: CoaB-like appears in the current release, SCOPe 2.08