Lineage for Species: Cryptosporidium hominis [TaxId: 237895]

  1. Root: SCOPe 2.01
  2. 968085Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1004246Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 1004247Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 1004248Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)
  6. 1004249Protein Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, DFR domain [53610] (2 species)
  7. 1004250Species Cryptosporidium hominis [TaxId:237895] [102636] (3 PDB entries)
    Uniprot Q5CGA3 Q27552

PDB entries in Species: Cryptosporidium hominis [TaxId: 237895]:

  1. Domain(s) for 1qzf:
    1. 1004256Domain d1qzfa1: 1qzf A:3-180 [96633]
      Other proteins in same PDB: d1qzfa2, d1qzfb2, d1qzfc2, d1qzfd2, d1qzfe2
      complexed with cb3, fol, ndp, ump
    2. 1004257Domain d1qzfb1: 1qzf B:3-180 [96635]
      Other proteins in same PDB: d1qzfa2, d1qzfb2, d1qzfc2, d1qzfd2, d1qzfe2
      complexed with cb3, fol, ndp, ump
    3. 1004258Domain d1qzfc1: 1qzf C:3-180 [96637]
      Other proteins in same PDB: d1qzfa2, d1qzfb2, d1qzfc2, d1qzfd2, d1qzfe2
      complexed with cb3, fol, ndp, ump
    4. 1004259Domain d1qzfd1: 1qzf D:3-180 [96639]
      Other proteins in same PDB: d1qzfa2, d1qzfb2, d1qzfc2, d1qzfd2, d1qzfe2
      complexed with cb3, fol, ndp, ump
    5. 1004260Domain d1qzfe1: 1qzf E:3-180 [96641]
      Other proteins in same PDB: d1qzfa2, d1qzfb2, d1qzfc2, d1qzfd2, d1qzfe2
      complexed with cb3, fol, ndp, ump
  2. Domain(s) for 1sej:
    1. 1004261Domain d1seja1: 1sej A:3-180 [105455]
      Other proteins in same PDB: d1seja2, d1sejb2, d1sejc2, d1sejd2, d1seje2
      complexed with f89, ndp, ump
    2. 1004262Domain d1sejb1: 1sej B:3-180 [105457]
      Other proteins in same PDB: d1seja2, d1sejb2, d1sejc2, d1sejd2, d1seje2
      complexed with f89, ndp, ump
    3. 1004263Domain d1sejc1: 1sej C:3-180 [105459]
      Other proteins in same PDB: d1seja2, d1sejb2, d1sejc2, d1sejd2, d1seje2
      complexed with f89, ndp, ump
    4. 1004264Domain d1sejd1: 1sej D:3-180 [105461]
      Other proteins in same PDB: d1seja2, d1sejb2, d1sejc2, d1sejd2, d1seje2
      complexed with f89, ndp, ump
    5. 1004265Domain d1seje1: 1sej E:3-180 [105463]
      Other proteins in same PDB: d1seja2, d1sejb2, d1sejc2, d1sejd2, d1seje2
      complexed with f89, ndp, ump
  3. Domain(s) for 2oip:
    1. 1004251Domain d2oipa1: 2oip A:3-180 [148784]
      Other proteins in same PDB: d2oipa2, d2oipb2, d2oipc2, d2oipd2, d2oipe2
      automatically matched to d1qzfa1
      complexed with cb3, mtx, ndp, ump; mutant
    2. 1004252Domain d2oipb1: 2oip B:3-180 [148786]
      Other proteins in same PDB: d2oipa2, d2oipb2, d2oipc2, d2oipd2, d2oipe2
      automatically matched to d1qzfa1
      complexed with cb3, mtx, ndp, ump; mutant
    3. 1004253Domain d2oipc1: 2oip C:3-180 [148788]
      Other proteins in same PDB: d2oipa2, d2oipb2, d2oipc2, d2oipd2, d2oipe2
      automatically matched to d1qzfa1
      complexed with cb3, mtx, ndp, ump; mutant
    4. 1004254Domain d2oipd1: 2oip D:3-180 [148790]
      Other proteins in same PDB: d2oipa2, d2oipb2, d2oipc2, d2oipd2, d2oipe2
      automatically matched to d1qzfa1
      complexed with cb3, mtx, ndp, ump; mutant
    5. 1004255Domain d2oipe1: 2oip E:3-180 [148792]
      Other proteins in same PDB: d2oipa2, d2oipb2, d2oipc2, d2oipd2, d2oipe2
      automatically matched to d1qzfa1
      complexed with cb3, mtx, ndp, ump; mutant

More info for Species Cryptosporidium hominis [TaxId:237895] from c.71.1.1 Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, DFR domain

Timeline for Species Cryptosporidium hominis [TaxId:237895] from c.71.1.1 Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, DFR domain: