Lineage for Species: Cryptosporidium hominis [TaxId: 237895]

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2477518Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2477519Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2477520Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)
  6. 2477521Protein Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, DFR domain [53610] (2 species)
  7. 2477522Species Cryptosporidium hominis [TaxId:237895] [102636] (15 PDB entries)
    Uniprot Q5CGA3 Q27552

PDB entries in Species: Cryptosporidium hominis [TaxId: 237895]:

  1. Domain(s) for 1qzf:
    1. 2477523Domain d1qzfa1: 1qzf A:3-180 [96633]
      Other proteins in same PDB: d1qzfa2, d1qzfb2, d1qzfc2, d1qzfd2, d1qzfe2
      complexed with cb3, fol, ndp, ump
    2. 2477524Domain d1qzfb1: 1qzf B:3-180 [96635]
      Other proteins in same PDB: d1qzfa2, d1qzfb2, d1qzfc2, d1qzfd2, d1qzfe2
      complexed with cb3, fol, ndp, ump
    3. 2477525Domain d1qzfc1: 1qzf C:3-180 [96637]
      Other proteins in same PDB: d1qzfa2, d1qzfb2, d1qzfc2, d1qzfd2, d1qzfe2
      complexed with cb3, fol, ndp, ump
    4. 2477526Domain d1qzfd1: 1qzf D:3-180 [96639]
      Other proteins in same PDB: d1qzfa2, d1qzfb2, d1qzfc2, d1qzfd2, d1qzfe2
      complexed with cb3, fol, ndp, ump
    5. 2477527Domain d1qzfe1: 1qzf E:3-180 [96641]
      Other proteins in same PDB: d1qzfa2, d1qzfb2, d1qzfc2, d1qzfd2, d1qzfe2
      complexed with cb3, fol, ndp, ump
  2. Domain(s) for 1sej:
    1. 2477533Domain d1seja1: 1sej A:3-180 [105455]
      Other proteins in same PDB: d1seja2, d1sejb2, d1sejc2, d1sejd2, d1seje2
      complexed with f89, ndp, ump
    2. 2477534Domain d1sejb1: 1sej B:3-180 [105457]
      Other proteins in same PDB: d1seja2, d1sejb2, d1sejc2, d1sejd2, d1seje2
      complexed with f89, ndp, ump
    3. 2477535Domain d1sejc1: 1sej C:3-180 [105459]
      Other proteins in same PDB: d1seja2, d1sejb2, d1sejc2, d1sejd2, d1seje2
      complexed with f89, ndp, ump
    4. 2477536Domain d1sejd1: 1sej D:3-180 [105461]
      Other proteins in same PDB: d1seja2, d1sejb2, d1sejc2, d1sejd2, d1seje2
      complexed with f89, ndp, ump
    5. 2477537Domain d1seje1: 1sej E:3-180 [105463]
      Other proteins in same PDB: d1seja2, d1sejb2, d1sejc2, d1sejd2, d1seje2
      complexed with f89, ndp, ump
  3. Domain(s) for 4q0e:
    1. 2477528Domain d4q0ea1: 4q0e A:3-178 [260370]
      Other proteins in same PDB: d4q0ea2, d4q0eb2, d4q0ec2, d4q0ed2, d4q0ee2
      automated match to d1seja1
      complexed with 2xb, ndp, ufp
    2. 2477529Domain d4q0eb1: 4q0e B:3-178 [260368]
      Other proteins in same PDB: d4q0ea2, d4q0eb2, d4q0ec2, d4q0ed2, d4q0ee2
      automated match to d1seja1
      complexed with 2xb, ndp, ufp
    3. 2477530Domain d4q0ec1: 4q0e C:3-178 [260372]
      Other proteins in same PDB: d4q0ea2, d4q0eb2, d4q0ec2, d4q0ed2, d4q0ee2
      automated match to d1seja1
      complexed with 2xb, ndp, ufp
    4. 2477531Domain d4q0ed1: 4q0e D:3-178 [260376]
      Other proteins in same PDB: d4q0ea2, d4q0eb2, d4q0ec2, d4q0ed2, d4q0ee2
      automated match to d1seja1
      complexed with 2xb, ndp, ufp
    5. 2477532Domain d4q0ee1: 4q0e E:3-178 [260374]
      Other proteins in same PDB: d4q0ea2, d4q0eb2, d4q0ec2, d4q0ed2, d4q0ee2
      automated match to d1seja1
      complexed with 2xb, ndp, ufp
  4. Domain(s) for 6pf7:
    1. 3075001Domain d6pf7d1: 6pf7 D:3-180 [375063]
      Other proteins in same PDB: d6pf7a2, d6pf7b2, d6pf7c2, d6pf7d2, d6pf7e2
      automated match to d1qzfa1
      complexed with mtx, ndp, og7, so4, ufp
    2. 3075003Domain d6pf7a1: 6pf7 A:3-180 [375065]
      Other proteins in same PDB: d6pf7a2, d6pf7b2, d6pf7c2, d6pf7d2, d6pf7e2
      automated match to d1qzfa1
      complexed with mtx, ndp, og7, so4, ufp
    3. 3075049Domain d6pf7b1: 6pf7 B:3-180 [375111]
      Other proteins in same PDB: d6pf7a2, d6pf7b2, d6pf7c2, d6pf7d2, d6pf7e2
      automated match to d1qzfa1
      complexed with mtx, ndp, og7, so4, ufp
    4. 3075067Domain d6pf7e1: 6pf7 E:3-180 [375129]
      Other proteins in same PDB: d6pf7a2, d6pf7b2, d6pf7c2, d6pf7d2, d6pf7e2
      automated match to d1qzfa1
      complexed with mtx, ndp, og7, so4, ufp
    5. 3075076Domain d6pf7c1: 6pf7 C:3-180 [375138]
      Other proteins in same PDB: d6pf7a2, d6pf7b2, d6pf7c2, d6pf7d2, d6pf7e2
      automated match to d1qzfa1
      complexed with mtx, ndp, og7, so4, ufp
  5. Domain(s) for 6pf8:
    1. 3074982Domain d6pf8e1: 6pf8 E:3-179 [375044]
      Other proteins in same PDB: d6pf8a2, d6pf8b2, d6pf8c2, d6pf8d2, d6pf8e2
      automated match to d1qzfa1
      complexed with mtx, ndp, oe7, ufp
    2. 3075014Domain d6pf8a1: 6pf8 A:3-179 [375076]
      Other proteins in same PDB: d6pf8a2, d6pf8b2, d6pf8c2, d6pf8d2, d6pf8e2
      automated match to d1qzfa1
      complexed with mtx, ndp, oe7, ufp
    3. 3075033Domain d6pf8d1: 6pf8 D:3-179 [375095]
      Other proteins in same PDB: d6pf8a2, d6pf8b2, d6pf8c2, d6pf8d2, d6pf8e2
      automated match to d1qzfa1
      complexed with mtx, ndp, oe7, ufp
    4. 3075059Domain d6pf8c1: 6pf8 C:3-178 [375121]
      Other proteins in same PDB: d6pf8a2, d6pf8b2, d6pf8c2, d6pf8d2, d6pf8e2
      automated match to d1qzfa1
      complexed with mtx, ndp, oe7, ufp
    5. 3075072Domain d6pf8b1: 6pf8 B:3-179 [375134]
      Other proteins in same PDB: d6pf8a2, d6pf8b2, d6pf8c2, d6pf8d2, d6pf8e2
      automated match to d1qzfa1
      complexed with mtx, ndp, oe7, ufp
  6. Domain(s) for 6pf9:
    1. 3074984Domain d6pf9e1: 6pf9 E:3-178 [375046]
      Other proteins in same PDB: d6pf9a2, d6pf9b2, d6pf9c2, d6pf9d2, d6pf9e2
      automated match to d1qzfa1
      complexed with mtx, ndp, of7, so4, ufp
    2. 3075005Domain d6pf9a1: 6pf9 A:3-179 [375067]
      Other proteins in same PDB: d6pf9a2, d6pf9b2, d6pf9c2, d6pf9d2, d6pf9e2
      automated match to d1qzfa1
      complexed with mtx, ndp, of7, so4, ufp
    3. 3075010Domain d6pf9d1: 6pf9 D:3-179 [375072]
      Other proteins in same PDB: d6pf9a2, d6pf9b2, d6pf9c2, d6pf9d2, d6pf9e2
      automated match to d1qzfa1
      complexed with mtx, ndp, of7, so4, ufp
    4. 3075031Domain d6pf9c1: 6pf9 C:3-179 [375093]
      Other proteins in same PDB: d6pf9a2, d6pf9b2, d6pf9c2, d6pf9d2, d6pf9e2
      automated match to d1qzfa1
      complexed with mtx, ndp, of7, so4, ufp
    5. 3075046Domain d6pf9b1: 6pf9 B:3-179 [375108]
      Other proteins in same PDB: d6pf9a2, d6pf9b2, d6pf9c2, d6pf9d2, d6pf9e2
      automated match to d1qzfa1
      complexed with mtx, ndp, of7, so4, ufp
  7. Domain(s) for 6pfa:
    1. 3074970Domain d6pfab1: 6pfa B:3-179 [375032]
      Other proteins in same PDB: d6pfaa2, d6pfab2, d6pfac2, d6pfad2, d6pfae2
      automated match to d1qzfa1
      complexed with mtx, ndp, of4, so4, ufp
    2. 3074991Domain d6pfae1: 6pfa E:3-179 [375053]
      Other proteins in same PDB: d6pfaa2, d6pfab2, d6pfac2, d6pfad2, d6pfae2
      automated match to d1qzfa1
      complexed with mtx, ndp, of4, so4, ufp
    3. 3074999Domain d6pfac1: 6pfa C:3-178 [375061]
      Other proteins in same PDB: d6pfaa2, d6pfab2, d6pfac2, d6pfad2, d6pfae2
      automated match to d1qzfa1
      complexed with mtx, ndp, of4, so4, ufp
    4. 3075078Domain d6pfad1: 6pfa D:3-179 [375140]
      Other proteins in same PDB: d6pfaa2, d6pfab2, d6pfac2, d6pfad2, d6pfae2
      automated match to d1qzfa1
      complexed with mtx, ndp, of4, so4, ufp
    5. 3075091Domain d6pfaa1: 6pfa A:3-179 [375153]
      Other proteins in same PDB: d6pfaa2, d6pfab2, d6pfac2, d6pfad2, d6pfae2
      automated match to d1qzfa1
      complexed with mtx, ndp, of4, so4, ufp
  8. Domain(s) for 6pfb:
    1. 3074976Domain d6pfbe1: 6pfb E:3-178 [375038]
      Other proteins in same PDB: d6pfba2, d6pfbb2, d6pfbc2, d6pfbd2, d6pfbe2
      automated match to d1qzfa1
      complexed with mtx, ndp, og4, ufp
    2. 3074986Domain d6pfba1: 6pfb A:3-178 [375048]
      Other proteins in same PDB: d6pfba2, d6pfbb2, d6pfbc2, d6pfbd2, d6pfbe2
      automated match to d1qzfa1
      complexed with mtx, ndp, og4, ufp
    3. 3074995Domain d6pfbc1: 6pfb C:3-179 [375057]
      Other proteins in same PDB: d6pfba2, d6pfbb2, d6pfbc2, d6pfbd2, d6pfbe2
      automated match to d1qzfa1
      complexed with mtx, ndp, og4, ufp
    4. 3075012Domain d6pfbd1: 6pfb D:3-179 [375074]
      Other proteins in same PDB: d6pfba2, d6pfbb2, d6pfbc2, d6pfbd2, d6pfbe2
      automated match to d1qzfa1
      complexed with mtx, ndp, og4, ufp
    5. 3075095Domain d6pfbb1: 6pfb B:3-178 [375157]
      Other proteins in same PDB: d6pfba2, d6pfbb2, d6pfbc2, d6pfbd2, d6pfbe2
      automated match to d1qzfa1
      complexed with mtx, ndp, og4, ufp
  9. Domain(s) for 6pfc:
    1. 3075753Domain d6pfca1: 6pfc A:3-179 [375815]
      Other proteins in same PDB: d6pfca2, d6pfcb2, d6pfcc2, d6pfcd2, d6pfce2
      automated match to d1qzfa1
      complexed with mtx, ndp, oed, ufp
    2. 3075757Domain d6pfcb1: 6pfc B:3-179 [375819]
      Other proteins in same PDB: d6pfca2, d6pfcb2, d6pfcc2, d6pfcd2, d6pfce2
      automated match to d1qzfa1
      complexed with mtx, ndp, oed, ufp
    3. 3075759Domain d6pfce1: 6pfc E:3-179 [375821]
      Other proteins in same PDB: d6pfca2, d6pfcb2, d6pfcc2, d6pfcd2, d6pfce2
      automated match to d1qzfa1
      complexed with mtx, ndp, oed, ufp
    4. 3075765Domain d6pfcc1: 6pfc C:3-179 [375827]
      Other proteins in same PDB: d6pfca2, d6pfcb2, d6pfcc2, d6pfcd2, d6pfce2
      automated match to d1qzfa1
      complexed with mtx, ndp, oed, ufp
    5. 3075781Domain d6pfcd1: 6pfc D:3-179 [375843]
      Other proteins in same PDB: d6pfca2, d6pfcb2, d6pfcc2, d6pfcd2, d6pfce2
      automated match to d1qzfa1
      complexed with mtx, ndp, oed, ufp
  10. Domain(s) for 6pfe:
    1. 3074972Domain d6pfea1: 6pfe A:3-179 [375034]
      Other proteins in same PDB: d6pfea2, d6pfeb2, d6pfec2, d6pfed2, d6pfee2
      automated match to d1qzfa1
      complexed with mtx, ndp, oea, ufp
    2. 3074978Domain d6pfec1: 6pfe C:3-180 [375040]
      Other proteins in same PDB: d6pfea2, d6pfeb2, d6pfec2, d6pfed2, d6pfee2
      automated match to d1qzfa1
      complexed with mtx, ndp, oea, ufp
    3. 3075020Domain d6pfed1: 6pfe D:3-180 [375082]
      Other proteins in same PDB: d6pfea2, d6pfeb2, d6pfec2, d6pfed2, d6pfee2
      automated match to d1qzfa1
      complexed with mtx, ndp, oea, ufp
    4. 3075116Domain d6pfee1: 6pfe E:3-178 [375178]
      Other proteins in same PDB: d6pfea2, d6pfeb2, d6pfec2, d6pfed2, d6pfee2
      automated match to d1qzfa1
      complexed with mtx, ndp, oea, ufp
    5. 3075172Domain d6pfeb1: 6pfe B:3-179 [375234]
      Other proteins in same PDB: d6pfea2, d6pfeb2, d6pfec2, d6pfed2, d6pfee2
      automated match to d1qzfa1
      complexed with mtx, ndp, oea, ufp
  11. Domain(s) for 6pff:
    1. 3075029Domain d6pffa1: 6pff A:3-179 [375091]
      Other proteins in same PDB: d6pffa2, d6pffb2, d6pffc2, d6pffd2, d6pffe2
      automated match to d1qzfa1
      complexed with mtx, ndp, og1, so4, ufp
    2. 3075065Domain d6pffb1: 6pff B:3-179 [375127]
      Other proteins in same PDB: d6pffa2, d6pffb2, d6pffc2, d6pffd2, d6pffe2
      automated match to d1qzfa1
      complexed with mtx, ndp, og1, so4, ufp
    3. 3075085Domain d6pffc1: 6pff C:3-179 [375147]
      Other proteins in same PDB: d6pffa2, d6pffb2, d6pffc2, d6pffd2, d6pffe2
      automated match to d1qzfa1
      complexed with mtx, ndp, og1, so4, ufp
    4. 3075087Domain d6pffd1: 6pff D:3-179 [375149]
      Other proteins in same PDB: d6pffa2, d6pffb2, d6pffc2, d6pffd2, d6pffe2
      automated match to d1qzfa1
      complexed with mtx, ndp, og1, so4, ufp
    5. 3075122Domain d6pffe1: 6pff E:3-179 [375184]
      Other proteins in same PDB: d6pffa2, d6pffb2, d6pffc2, d6pffd2, d6pffe2
      automated match to d1qzfa1
      complexed with mtx, ndp, og1, so4, ufp
  12. Domain(s) for 6pfg:
    1. 3074966Domain d6pfga1: 6pfg A:3-178 [375028]
      Other proteins in same PDB: d6pfga2, d6pfgb2, d6pfgc2, d6pfgd2, d6pfge2
      automated match to d1qzfa1
      complexed with mtx, ndp, ofj, so4, ufp
    2. 3074968Domain d6pfgc1: 6pfg C:3-179 [375030]
      Other proteins in same PDB: d6pfga2, d6pfgb2, d6pfgc2, d6pfgd2, d6pfge2
      automated match to d1qzfa1
      complexed with mtx, ndp, ofj, so4, ufp
    3. 3075007Domain d6pfgb1: 6pfg B:3-179 [375069]
      Other proteins in same PDB: d6pfga2, d6pfgb2, d6pfgc2, d6pfgd2, d6pfge2
      automated match to d1qzfa1
      complexed with mtx, ndp, ofj, so4, ufp
    4. 3075037Domain d6pfgd1: 6pfg D:3-179 [375099]
      Other proteins in same PDB: d6pfga2, d6pfgb2, d6pfgc2, d6pfgd2, d6pfge2
      automated match to d1qzfa1
      complexed with mtx, ndp, ofj, so4, ufp
    5. 3075039Domain d6pfge1: 6pfg E:3-179 [375101]
      Other proteins in same PDB: d6pfga2, d6pfgb2, d6pfgc2, d6pfgd2, d6pfge2
      automated match to d1qzfa1
      complexed with mtx, ndp, ofj, so4, ufp
  13. Domain(s) for 6pfh:
    1. 3074974Domain d6pfhd1: 6pfh D:3-180 [375036]
      Other proteins in same PDB: d6pfha2, d6pfhb2, d6pfhc2, d6pfhd2, d6pfhe2
      automated match to d1qzfa1
      complexed with mtx, ndp, ofd, ufp
    2. 3074988Domain d6pfha1: 6pfh A:3-180 [375050]
      Other proteins in same PDB: d6pfha2, d6pfhb2, d6pfhc2, d6pfhd2, d6pfhe2
      automated match to d1qzfa1
      complexed with mtx, ndp, ofd, ufp
    3. 3075024Domain d6pfhc1: 6pfh C:3-179 [375086]
      Other proteins in same PDB: d6pfha2, d6pfhb2, d6pfhc2, d6pfhd2, d6pfhe2
      automated match to d1qzfa1
      complexed with mtx, ndp, ofd, ufp
    4. 3075083Domain d6pfhb1: 6pfh B:3-179 [375145]
      Other proteins in same PDB: d6pfha2, d6pfhb2, d6pfhc2, d6pfhd2, d6pfhe2
      automated match to d1qzfa1
      complexed with mtx, ndp, ofd, ufp
    5. 3075103Domain d6pfhe1: 6pfh E:3-179 [375165]
      Other proteins in same PDB: d6pfha2, d6pfhb2, d6pfhc2, d6pfhd2, d6pfhe2
      automated match to d1qzfa1
      complexed with mtx, ndp, ofd, ufp
  14. Domain(s) for 6pfi:
    1. 3074993Domain d6pfie1: 6pfi E:3-179 [375055]
      Other proteins in same PDB: d6pfia2, d6pfib2, d6pfic2, d6pfid2, d6pfie2
      automated match to d1qzfa1
      complexed with mtx, ndp, oep, ufp
    2. 3074997Domain d6pfic1: 6pfi C:3-179 [375059]
      Other proteins in same PDB: d6pfia2, d6pfib2, d6pfic2, d6pfid2, d6pfie2
      automated match to d1qzfa1
      complexed with mtx, ndp, oep, ufp
    3. 3075022Domain d6pfib1: 6pfi B:3-180 [375084]
      Other proteins in same PDB: d6pfia2, d6pfib2, d6pfic2, d6pfid2, d6pfie2
      automated match to d1qzfa1
      complexed with mtx, ndp, oep, ufp
    4. 3075044Domain d6pfia1: 6pfi A:3-179 [375106]
      Other proteins in same PDB: d6pfia2, d6pfib2, d6pfic2, d6pfid2, d6pfie2
      automated match to d1qzfa1
      complexed with mtx, ndp, oep, ufp
    5. 3075128Domain d6pfid1: 6pfi D:3-180 [375190]
      Other proteins in same PDB: d6pfia2, d6pfib2, d6pfic2, d6pfid2, d6pfie2
      automated match to d1qzfa1
      complexed with mtx, ndp, oep, ufp
  15. Domain(s) for 6wep:
    1. 3087953Domain d6wepb1: 6wep B:3-178 [388015]
      Other proteins in same PDB: d6wepa2, d6wepb2
      automated match to d1qzfa1
      complexed with mtx, ndp
    2. 3087957Domain d6wepa1: 6wep A:3-178 [388019]
      Other proteins in same PDB: d6wepa2, d6wepb2
      automated match to d1qzfa1
      complexed with mtx, ndp

More info for Species Cryptosporidium hominis [TaxId:237895] from c.71.1.1 Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, DFR domain

Timeline for Species Cryptosporidium hominis [TaxId:237895] from c.71.1.1 Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, DFR domain: