Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily) 3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes |
Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (25 families) division into families based on beta-sheet topologies |
Family c.37.1.12: ABC transporter ATPase domain-like [52686] (24 proteins) there are two additional subdomains inserted into the central core that has a RecA-like topology |
Protein Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain [102378] (2 species) |
Human (Homo sapiens) [TaxId:9606] [117543] (8 PDB entries) Uniprot P13569 389-671 |
Domain d1xmia_: 1xmi A: [115489] complexed with atp, mg |
Domain d1xmib_: 1xmi B: [115490] complexed with atp, mg |
Domain d1xmic_: 1xmi C: [115491] complexed with atp, mg |
Domain d1xmid_: 1xmi D: [115492] complexed with atp, mg |
Domain d1xmie_: 1xmi E: [115493] complexed with atp, mg |
Domain d1xmja_: 1xmj A: [115494] complexed with atp, mg |
Domain d2bboa_: 2bbo A: [163031] automated match to d1xmja_ complexed with atp, mg |
Domain d2bbsa_: 2bbs A: [163032] automated match to d1xmid_ complexed with atp, mg; mutant |
Domain d2bbsb_: 2bbs B: [163033] automated match to d1xmid_ complexed with atp, mg; mutant |
Domain d2bbta_: 2bbt A: [163034] automated match to d1xmid_ complexed with atp, mg; mutant |
Domain d2bbtb_: 2bbt B: [163035] automated match to d1xmid_ complexed with atp, mg; mutant |
Domain d2pzea_: 2pze A: [231179] automated match to d2pzeb_ complexed with atp, mg |
Domain d2pzeb_: 2pze B: [205696] automated match to d1l2ta_ complexed with atp, mg |
Domain d2pzfa_: 2pzf A: [231180] automated match to d2pzfb_ complexed with atp, mg |
Domain d2pzfb_: 2pzf B: [205697] automated match to d1l2ta_ complexed with atp, mg |
Domain d2pzga_: 2pzg A: [231181] automated match to d2pzgb_ complexed with atp, gol, mg |
Domain d2pzgb_: 2pzg B: [205698] automated match to d1l2ta_ complexed with atp, gol, mg |
Mouse (Mus musculus) [TaxId:10090] [102379] (9 PDB entries) Uniprot P26361 390-670 |
Domain d1q3ha_: 1q3h A: [95688] complexed with acy, anp, mg |
Domain d1q3hb_: 1q3h B: [95689] complexed with acy, anp, mg |
Domain d1q3hc_: 1q3h C: [95690] complexed with acy, anp, mg |
Domain d1q3hd_: 1q3h D: [95691] complexed with acy, anp, mg |
Domain d1r0wa_: 1r0w A: [96754] complexed with acy |
Domain d1r0wb_: 1r0w B: [96755] complexed with acy |
Domain d1r0wc_: 1r0w C: [96756] complexed with acy |
Domain d1r0wd_: 1r0w D: [96757] complexed with acy |
Domain d1r0xa_: 1r0x A: [96758] complexed with acy, atp, mg |
Domain d1r0xb_: 1r0x B: [96759] complexed with acy, atp, mg |
Domain d1r0xc_: 1r0x C: [96760] complexed with acy, atp, mg |
Domain d1r0xd_: 1r0x D: [96761] complexed with acy, atp, mg |
Domain d1r0ya_: 1r0y A: [96762] complexed with acy, adp |
Domain d1r0yb_: 1r0y B: [96763] complexed with acy, adp |
Domain d1r0yc_: 1r0y C: [96764] complexed with acy, adp |
Domain d1r0yd_: 1r0y D: [96765] complexed with acy, adp |
Domain d1r0za_: 1r0z A: [96766] complexed with acy, atp, mg |
Domain d1r0zb_: 1r0z B: [96767] complexed with acy, atp, mg |
Domain d1r0zc_: 1r0z C: [96768] complexed with acy, atp, mg |
Domain d1r0zd_: 1r0z D: [96769] complexed with acy, atp, mg |
Domain d1r10a_: 1r10 A: [96770] complexed with acy, atp, mg |
Domain d1r10b_: 1r10 B: [96771] complexed with acy, atp, mg |
Domain d1xf9a_: 1xf9 A: [115245] complexed with acy, atp, mg; mutant |
Domain d1xf9b_: 1xf9 B: [115246] complexed with acy, atp, mg; mutant |
Domain d1xf9c_: 1xf9 C: [115247] complexed with acy, atp, mg; mutant |
Domain d1xf9d_: 1xf9 D: [115248] complexed with acy, atp, mg; mutant |
Domain d1xfaa_: 1xfa A: [115249] complexed with acy, atp, cl, mg; mutant |
Domain d1xfab_: 1xfa B: [115250] complexed with acy, atp, cl, mg; mutant |
Domain d3si7a_: 3si7 A: [185410] automated match to d1q3hc_ complexed with act, atp, mg; mutant |
Domain d3si7b_: 3si7 B: [185411] automated match to d1q3hc_ complexed with act, atp, mg; mutant |
Domain d3si7c_: 3si7 C: [185412] automated match to d1q3hc_ complexed with act, atp, mg; mutant |
Domain d3si7d_: 3si7 D: [185413] automated match to d1q3hc_ complexed with act, atp, mg; mutant |
Timeline for Protein Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain from c.37.1.12: ABC transporter ATPase domain-like: