SCOP 1.73: Protein: Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain

Lineage for Protein: Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain

Root: SCOP 1.73
Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (24 families)
division into families based on beta-sheet topologies
Family c.37.1.12: ABC transporter ATPase domain-like [52686] (20 proteins)
there are two additional subdomains inserted into the central core that has a RecA-like topology
Protein Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain [102378] (2 species)

Species:

Human (Homo sapiens) [TaxId:9606] [117543] (2 PDB entries)
1. Domains for 1xmi:
  1. Domain d1xmia_: 1xmi A: [115489]
  2. Domain d1xmib_: 1xmi B: [115490]
  3. Domain d1xmic_: 1xmi C: [115491]
  4. Domain d1xmid_: 1xmi D: [115492]
  5. Domain d1xmie_: 1xmi E: [115493]
    complexed with atp, mg; mutant
2. Domain for 1xmj:
  - Domain d1xmja_: 1xmj A: [115494]
    complexed with atp, mg; mutant
Mouse (Mus musculus) [TaxId:10090] [102379] (8 PDB entries)
1. Domains for 1q3h:
  1. Domain d1q3ha_: 1q3h A: [95688]
  2. Domain d1q3hb_: 1q3h B: [95689]
  3. Domain d1q3hc_: 1q3h C: [95690]
  4. Domain d1q3hd_: 1q3h D: [95691]
    complexed with acy, anp, mg
2. Domains for 1r0w:
  1. Domain d1r0wa_: 1r0w A: [96754]
  2. Domain d1r0wb_: 1r0w B: [96755]
  3. Domain d1r0wc_: 1r0w C: [96756]
  4. Domain d1r0wd_: 1r0w D: [96757]
    complexed with acy
3. Domains for 1r0x:
  1. Domain d1r0xa_: 1r0x A: [96758]
  2. Domain d1r0xb_: 1r0x B: [96759]
  3. Domain d1r0xc_: 1r0x C: [96760]
  4. Domain d1r0xd_: 1r0x D: [96761]
    complexed with acy, atp, mg
4. Domains for 1r0y:
  1. Domain d1r0ya_: 1r0y A: [96762]
  2. Domain d1r0yb_: 1r0y B: [96763]
  3. Domain d1r0yc_: 1r0y C: [96764]
  4. Domain d1r0yd_: 1r0y D: [96765]
    complexed with acy, adp
5. Domains for 1r0z:
  1. Domain d1r0za_: 1r0z A: [96766]
  2. Domain d1r0zb_: 1r0z B: [96767]
  3. Domain d1r0zc_: 1r0z C: [96768]
  4. Domain d1r0zd_: 1r0z D: [96769]
    complexed with acy, atp, mg
6. Domains for 1r10:
  1. Domain d1r10a_: 1r10 A: [96770]
  2. Domain d1r10b_: 1r10 B: [96771]
    complexed with acy, atp, mg
7. Domains for 1xf9:
  1. Domain d1xf9a_: 1xf9 A: [115245]
  2. Domain d1xf9b_: 1xf9 B: [115246]
  3. Domain d1xf9c_: 1xf9 C: [115247]
  4. Domain d1xf9d_: 1xf9 D: [115248]
    complexed with acy, atp, mg; mutant
8. Domains for 1xfa:
  1. Domain d1xfaa_: 1xfa A: [115249]
  2. Domain d1xfab_: 1xfa B: [115250]
    complexed with acy, atp, cl, mg; mutant

More info for Protein Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain from c.37.1.12: ABC transporter ATPase domain-like

Timeline for Protein Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain from c.37.1.12: ABC transporter ATPase domain-like:

Protein Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain from c.37.1.12: ABC transporter ATPase domain-like first appeared in SCOP 1.67
Protein Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain from c.37.1.12: ABC transporter ATPase domain-like appears in SCOP 1.71
Protein Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain from c.37.1.12: ABC transporter ATPase domain-like appears in SCOP 1.75
Protein Cystic fibrosis transmembrane conductance regulator, CFTR, nucleotide-binding domain from c.37.1.12: ABC transporter ATPase domain-like appears in the current release, SCOPe 2.08