Lineage for Species: Thermus thermophilus [TaxId: 274]

  1. Root: SCOPe 2.05
  2. 1815291Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 1844143Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 1844144Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (9 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 1844315Family c.36.1.7: Branched-chain alpha-keto acid dehydrogenase Pyr module [88741] (5 proteins)
    parent family to TK and PFOR
    heterodimeric protein related to TK; alpha-subunit is the PP module and the N-terminal domain of beta-subunit is the Pyr module
    automatically mapped to Pfam PF02779
  6. 1844319Protein Branched-chain alpha-keto acid dehydrogenase, Pyr module [88742] (2 species)
  7. 1844344Species Thermus thermophilus [TaxId:274] [102332] (4 PDB entries)

PDB entries in Species: Thermus thermophilus [TaxId: 274]:

  1. Domain(s) for 1um9:
    1. 1844349Domain d1um9b1: 1um9 B:2-187 [99582]
      Other proteins in same PDB: d1um9a_, d1um9b2, d1um9c_, d1um9d2
      complexed with so4
    2. 1844350Domain d1um9d1: 1um9 D:2-187 [99585]
      Other proteins in same PDB: d1um9a_, d1um9b2, d1um9c_, d1um9d2
      complexed with so4
  2. Domain(s) for 1umb:
    1. 1844347Domain d1umbb1: 1umb B:2-187 [99588]
      Other proteins in same PDB: d1umba_, d1umbb2, d1umbc_, d1umbd2
      complexed with mg, tdp
    2. 1844348Domain d1umbd1: 1umb D:2-187 [99591]
      Other proteins in same PDB: d1umba_, d1umbb2, d1umbc_, d1umbd2
      complexed with mg, tdp
  3. Domain(s) for 1umc:
    1. 1844351Domain d1umcb1: 1umc B:2-187 [99594]
      Other proteins in same PDB: d1umca_, d1umcb2, d1umcc_, d1umcd2
      complexed with 4mv, mg, tdp
    2. 1844352Domain d1umcd1: 1umc D:2-187 [99597]
      Other proteins in same PDB: d1umca_, d1umcb2, d1umcc_, d1umcd2
      complexed with 4mv, mg, tdp
  4. Domain(s) for 1umd:
    1. 1844345Domain d1umdb1: 1umd B:2-187 [99600]
      Other proteins in same PDB: d1umda_, d1umdb2, d1umdc_, d1umdd2
      complexed with coi, mg, tdp
    2. 1844346Domain d1umdd1: 1umd D:2-187 [99603]
      Other proteins in same PDB: d1umda_, d1umdb2, d1umdc_, d1umdd2
      complexed with coi, mg, tdp

More info for Species Thermus thermophilus [TaxId:274] from c.36.1.7 Branched-chain alpha-keto acid dehydrogenase, Pyr module

Timeline for Species Thermus thermophilus [TaxId:274] from c.36.1.7 Branched-chain alpha-keto acid dehydrogenase, Pyr module: