SCOPe 2.01: Protein: Carboxyethylarginine synthase

Lineage for Protein: Carboxyethylarginine synthase

Root: SCOPe 2.01
Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465

Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families)

there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules

Family c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module [88724] (8 proteins)
the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpha/beta domain of Rossmann-like topology

Protein Carboxyethylarginine synthase [102330] (1 species)

Species:

Streptomyces clavuligerus [TaxId:1901] [102331] (6 PDB entries)

Domains for 1upa:
1. Domain d1upaa2: 1upa A:12-197 [99715]
  Other proteins in same PDB: d1upaa1, d1upaa3, d1upab1, d1upab3, d1upac1, d1upac3, d1upad1, d1upad3
  complexed with mg, so4, tpp
2. Domain d1upab2: 1upa B:12-197 [99718]
  Other proteins in same PDB: d1upaa1, d1upaa3, d1upab1, d1upab3, d1upac1, d1upac3, d1upad1, d1upad3
  complexed with mg, so4, tpp
3. Domain d1upac2: 1upa C:12-197 [99721]
  Other proteins in same PDB: d1upaa1, d1upaa3, d1upab1, d1upab3, d1upac1, d1upac3, d1upad1, d1upad3
  complexed with mg, so4, tpp
4. Domain d1upad2: 1upa D:12-197 [99724]
  Other proteins in same PDB: d1upaa1, d1upaa3, d1upab1, d1upab3, d1upac1, d1upac3, d1upad1, d1upad3
  complexed with mg, so4, tpp
Domains for 1upb:
1. Domain d1upba2: 1upb A:12-197 [99727]
  Other proteins in same PDB: d1upba1, d1upba3, d1upbb1, d1upbb3, d1upbc1, d1upbc3, d1upbd1, d1upbd3
  complexed with mg, so4, tpp
2. Domain d1upbb2: 1upb B:12-197 [99730]
  Other proteins in same PDB: d1upba1, d1upba3, d1upbb1, d1upbb3, d1upbc1, d1upbc3, d1upbd1, d1upbd3
  complexed with mg, so4, tpp
3. Domain d1upbc2: 1upb C:12-197 [99733]
  Other proteins in same PDB: d1upba1, d1upba3, d1upbb1, d1upbb3, d1upbc1, d1upbc3, d1upbd1, d1upbd3
  complexed with mg, so4, tpp
4. Domain d1upbd2: 1upb D:12-197 [99736]
  Other proteins in same PDB: d1upba1, d1upba3, d1upbb1, d1upbb3, d1upbc1, d1upbc3, d1upbd1, d1upbd3
  complexed with mg, so4, tpp
Domains for 1upc:
1. Domain d1upca2: 1upc A:12-197 [99739]
  Other proteins in same PDB: d1upca1, d1upca3, d1upcb1, d1upcb3, d1upcc1, d1upcc3, d1upcd1, d1upcd3, d1upce1, d1upce3, d1upcf1, d1upcf3
  complexed with mg, so4, tpp
2. Domain d1upcb2: 1upc B:12-197 [99742]
  Other proteins in same PDB: d1upca1, d1upca3, d1upcb1, d1upcb3, d1upcc1, d1upcc3, d1upcd1, d1upcd3, d1upce1, d1upce3, d1upcf1, d1upcf3
  complexed with mg, so4, tpp
3. Domain d1upcc2: 1upc C:12-197 [99745]
  Other proteins in same PDB: d1upca1, d1upca3, d1upcb1, d1upcb3, d1upcc1, d1upcc3, d1upcd1, d1upcd3, d1upce1, d1upce3, d1upcf1, d1upcf3
  complexed with mg, so4, tpp
4. Domain d1upcd2: 1upc D:12-197 [99748]
  Other proteins in same PDB: d1upca1, d1upca3, d1upcb1, d1upcb3, d1upcc1, d1upcc3, d1upcd1, d1upcd3, d1upce1, d1upce3, d1upcf1, d1upcf3
  complexed with mg, so4, tpp
5. Domain d1upce2: 1upc E:12-197 [99751]
  Other proteins in same PDB: d1upca1, d1upca3, d1upcb1, d1upcb3, d1upcc1, d1upcc3, d1upcd1, d1upcd3, d1upce1, d1upce3, d1upcf1, d1upcf3
  complexed with mg, so4, tpp
6. Domain d1upcf2: 1upc F:12-197 [99754]
  Other proteins in same PDB: d1upca1, d1upca3, d1upcb1, d1upcb3, d1upcc1, d1upcc3, d1upcd1, d1upcd3, d1upce1, d1upce3, d1upcf1, d1upcf3
  complexed with mg, so4, tpp

Domains for 2iht:

Domain d2ihta2: 2iht A:12-197 [147686]
Other proteins in same PDB: d2ihta1, d2ihta3, d2ihtb1, d2ihtb3, d2ihtc1, d2ihtc3, d2ihtd1, d2ihtd3
automatically matched to d1upaa2
complexed with gol, mg, so4, tpp

Domain d2ihtb2: 2iht B:12-197 [147689]
Other proteins in same PDB: d2ihta1, d2ihta3, d2ihtb1, d2ihtb3, d2ihtc1, d2ihtc3, d2ihtd1, d2ihtd3
automatically matched to d1upaa2
complexed with gol, mg, so4, tpp

Domain d2ihtc2: 2iht C:12-197 [147692]
Other proteins in same PDB: d2ihta1, d2ihta3, d2ihtb1, d2ihtb3, d2ihtc1, d2ihtc3, d2ihtd1, d2ihtd3
automatically matched to d1upaa2
complexed with gol, mg, so4, tpp

Domain d2ihtd2: 2iht D:12-197 [147695]
Other proteins in same PDB: d2ihta1, d2ihta3, d2ihtb1, d2ihtb3, d2ihtc1, d2ihtc3, d2ihtd1, d2ihtd3
automatically matched to d1upaa2
complexed with gol, mg, so4, tpp

Domain for 2ihu:
- Domain d2ihua2: 2ihu A:12-197 [147698]
  Other proteins in same PDB: d2ihua1, d2ihua3
  automatically matched to d1upaa2
  complexed with gol, k, mg, tar, tp8, tp9
Domains for 2ihv:
1. Domain d2ihva2: 2ihv A:12-197 [147701]
  Other proteins in same PDB: d2ihva1, d2ihva3, d2ihvb1, d2ihvb3, d2ihvd1, d2ihvd3
  automatically matched to d1upaa2
  complexed with gva, k, mg, tpp
2. Domain d2ihvb2: 2ihv B:12-197 [147704]
  Other proteins in same PDB: d2ihva1, d2ihva3, d2ihvb1, d2ihvb3, d2ihvd1, d2ihvd3
  automatically matched to d1upaa2
  complexed with gva, k, mg, tpp
3. Domain d2ihvd2: 2ihv D:12-197 [147707]
  Other proteins in same PDB: d2ihva1, d2ihva3, d2ihvb1, d2ihvb3, d2ihvd1, d2ihvd3
  automatically matched to d1upaa2
  complexed with gva, k, mg, tpp

More info for Protein Carboxyethylarginine synthase from c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module

Timeline for Protein Carboxyethylarginine synthase from c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module:

Protein Carboxyethylarginine synthase from c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module first appeared in SCOP 1.67
Protein Carboxyethylarginine synthase from c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module appears in SCOP 1.75
Protein Carboxyethylarginine synthase from c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module appears in SCOPe 2.02
Protein Carboxyethylarginine synthase from c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module appears in the current release, SCOPe 2.08