SCOP 1.71: Protein: NAD-dependent deacetylase CobB

Root: SCOP 1.71
Class c: Alpha and beta proteins (a/b) [51349] (134 folds)
Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (5 families)
binds cofactor molecules in the opposite direction than classical Rossmann fold
Family c.31.1.5: Sir2 family of transcriptional regulators [63984] (5 proteins)
silent information regulator 2; contains insertion of a rubredoxin-like zinc finger domain
Protein NAD-dependent deacetylase CobB [102292] (1 species)

Escherichia coli [TaxId:562] [102293] (1 PDB entry)
- Domain for 1s5p:
  - Domain d1s5pa_: 1s5p A: [98569]
    complex with a acetylated substrate peptide, chain B
    complexed with zn

Timeline for Protein NAD-dependent deacetylase CobB from c.31.1.5: Sir2 family of transcriptional regulators:

Protein NAD-dependent deacetylase CobB from c.31.1.5: Sir2 family of transcriptional regulators first appeared in SCOP 1.67
Protein NAD-dependent deacetylase CobB from c.31.1.5: Sir2 family of transcriptional regulators appears in SCOP 1.69
Protein NAD-dependent deacetylase CobB from c.31.1.5: Sir2 family of transcriptional regulators appears in SCOP 1.73
Protein NAD-dependent deacetylase CobB from c.31.1.5: Sir2 family of transcriptional regulators appears in the current release, SCOPe 2.08