SCOPe 2.05: Family c.8.8.1: Putative cyclase

Lineage for Family c.8.8.1: Putative cyclase

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.8: The "swivelling" beta/beta/alpha domain [52008] (10 superfamilies)
   3 layers: b/b/a; the central sheet is parallel, and the other one is antiparallel; there are some variations in topology
   this domain is thought to be mobile in most multi-domain proteins known to contain it

4. Superfamily c.8.8: Putative cyclase [102198] (2 families)
   contains mixed beta-sheet barrel, closed n=7, S=10

5. Family c.8.8.1: Putative cyclase [102199] (2 proteins)
   Pfam PF04199; COG1878: predicted metal-dependent hydrolase

Proteins:

1. Hypothetical protein MJ0783 [141972] (1 species)

   • Species Methanococcus jannaschii [TaxId:2190] [141973] (1 PDB entry)
     Uniprot Q58193 1-186

2. Unnamed protein [102200] (1 species)
   not in the sequence database yet; closest homologue is TTE1006 from Thermoanaerobacter tengcongensis

   • Species Bacillus stearothermophilus [TaxId:1422] [102201] (2 PDB entries)
     conflict: annotated in PDB as from Escherichia coli

More info for Family c.8.8.1: Putative cyclase

Timeline for Family c.8.8.1: Putative cyclase:

• Family c.8.8.1: Putative cyclase first appeared in SCOP 1.67
  
• Family c.8.8.1: Putative cyclase appears in SCOPe 2.04
  
• Family c.8.8.1: Putative cyclase appears in SCOPe 2.06
  
• Family c.8.8.1: Putative cyclase appears in the current release, SCOPe 2.08