SCOPe 2.08: Family c.2.1.12: Transcriptional repressor Rex, C-terminal domain

Lineage for Family c.2.1.12: Transcriptional repressor Rex, C-terminal domain

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.12: Transcriptional repressor Rex, C-terminal domain [102174] (2 proteins)
   automatically mapped to Pfam PF02629

Proteins:

1. Transcriptional repressor Rex, C-terminal domain [102175] (1 species)
   forms swapped dimer with C-terminal helices

   • Species Thermus aquaticus [TaxId:271] [102176] (3 PDB entries)
     Uniprot Q9X2V5
     CASP5

2. automated matches [346067] (1 species)
   not a true protein

   • Species Thermus thermophilus [TaxId:262724] [346276] (1 PDB entry)

More info for Family c.2.1.12: Transcriptional repressor Rex, C-terminal domain

Timeline for Family c.2.1.12: Transcriptional repressor Rex, C-terminal domain:

• Family c.2.1.12: Transcriptional repressor Rex, C-terminal domain first appeared in SCOP 1.67, called Family c.2.1.12: AT-rich DNA-binding protein p25, C-terminal domain
  
• Family c.2.1.12: Transcriptional repressor Rex, C-terminal domain appears in SCOPe 2.07