Lineage for Protein: Hydroxyisobutyrate dehydrogenase

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 685975Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 685976Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families) (S)
  5. 688157Family c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain [51868] (17 protein domains)
    the beta-sheet is extended to 8 strands, order 32145678; strands 7 & 8 are antiparallel to the rest
    C-terminal domains also show some similarity
  6. 688234Protein Hydroxyisobutyrate dehydrogenase [102171] (2 species)

Species:

  1. 688235Salmonella typhimurium [TaxId:90371] [110431] (1 PDB entry)
  2. 688237Thermus thermophilus [TaxId:274] [102172] (2 PDB entries)
    structural genomics
    1. Domains for 1wp4:
      1. 688242Domain d1wp4a2: 1wp4 A:2-157 [121136]
        Other proteins in same PDB: d1wp4a1, d1wp4b1, d1wp4c1, d1wp4d1
        automatically matched to d1j3vc2
        complexed with ndp, so4
      2. 688243Domain d1wp4b2: 1wp4 B:2-157 [121138]
        Other proteins in same PDB: d1wp4a1, d1wp4b1, d1wp4c1, d1wp4d1
        automatically matched to d1j3vc2
        complexed with ndp, so4
      3. 688244Domain d1wp4c2: 1wp4 C:2-157 [121140]
        Other proteins in same PDB: d1wp4a1, d1wp4b1, d1wp4c1, d1wp4d1
        automatically matched to d1j3vc2
        complexed with ndp, so4
      4. 688245Domain d1wp4d2: 1wp4 D:2-157 [121142]
        Other proteins in same PDB: d1wp4a1, d1wp4b1, d1wp4c1, d1wp4d1
        automatically matched to d1j3vc2
        complexed with ndp, so4
    2. Domains for 2cvz:
      1. 688238Domain d2cvza2: 2cvz A:2-157 [130891]
        Other proteins in same PDB: d2cvza1, d2cvzb1, d2cvzc1, d2cvzd1
        automatically matched to d1j3vc2
        complexed with ndp
      2. 688239Domain d2cvzb2: 2cvz B:2-157 [130893]
        Other proteins in same PDB: d2cvza1, d2cvzb1, d2cvzc1, d2cvzd1
        automatically matched to d1j3vc2
        complexed with ndp
      3. 688240Domain d2cvzc2: 2cvz C:2-157 [130895]
        Other proteins in same PDB: d2cvza1, d2cvzb1, d2cvzc1, d2cvzd1
        automatically matched to d1j3vc2
        complexed with ndp
      4. 688241Domain d2cvzd2: 2cvz D:2-157 [130897]
        Other proteins in same PDB: d2cvza1, d2cvzb1, d2cvzc1, d2cvzd1
        automatically matched to d1j3vc2
        complexed with ndp

More info for Protein Hydroxyisobutyrate dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain

Timeline for Protein Hydroxyisobutyrate dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain:

  • Protein Hydroxyisobutyrate dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain first appeared in SCOP 1.67
  • Protein Hydroxyisobutyrate dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain appears in SCOP 1.71
  • Protein Hydroxyisobutyrate dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain appears in SCOP 1.75
  • Protein Hydroxyisobutyrate dehydrogenase from c.2.1.6: 6-phosphogluconate dehydrogenase-like, N-terminal domain appears in the current release, SCOPe 2.07