Class c: Alpha and beta proteins (a/b) [51349] (130 folds) |
Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily) core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456 The nucleotide-binding modes of this and the next two folds/superfamilies are similar |
Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (11 families) |
Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (40 proteins) also known as short-chain dehydrogenases and SDR family parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7 |
Protein Halohydrin dehalogenase HheC [102153] (1 species) haloalcohol dehalogenase: evolved a new activity; lost the NAD-binding site |
Species Agrobacterium tumefaciens [TaxId:358] [102154] (3 PDB entries) |
Domain d1pwxa_: 1pwx A: [95262] |
Domain d1pwxb_: 1pwx B: [95263] |
Domain d1pwxc_: 1pwx C: [95264] |
Domain d1pwxd_: 1pwx D: [95265] complexed with br |
Domain d1pwza_: 1pwz A: [95267] |
Domain d1pwzb_: 1pwz B: [95268] complexed with cl, rso |
Domain d1px0a_: 1px0 A: [95269] |
Domain d1px0b_: 1px0 B: [95270] |
Domain d1px0c_: 1px0 C: [95271] |
Domain d1px0d_: 1px0 D: [95272] complexed with rpn |
Timeline for Species Agrobacterium tumefaciens [TaxId:358] from c.2.1.2 Halohydrin dehalogenase HheC: