SCOP 1.73: Protein: Halohydrin dehalogenase HheC

Lineage for Protein: Halohydrin dehalogenase HheC

Root: SCOP 1.73
Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
The nucleotide-binding modes of this and the next two folds/superfamilies are similar

Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (70 proteins)
also known as short-chain dehydrogenases and SDR family
parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

Protein Halohydrin dehalogenase HheC [102153] (1 species)
haloalcohol dehalogenase: evolved a new activity; lost the NAD-binding site

Species:

Agrobacterium tumefaciens [TaxId:358] [102154] (5 PDB entries)
1. Domains for 1pwx:
  1. Domain d1pwxa_: 1pwx A: [95262]
  2. Domain d1pwxb_: 1pwx B: [95263]
  3. Domain d1pwxc_: 1pwx C: [95264]
  4. Domain d1pwxd_: 1pwx D: [95265]
    complexed with br
2. Domains for 1pwz:
  1. Domain d1pwza_: 1pwz A: [95267]
  2. Domain d1pwzb_: 1pwz B: [95268]
    complexed with cl, rso
3. Domains for 1px0:
  1. Domain d1px0a_: 1px0 A: [95269]
  2. Domain d1px0b_: 1px0 B: [95270]
  3. Domain d1px0c_: 1px0 C: [95271]
  4. Domain d1px0d_: 1px0 D: [95272]
    complexed with rpn
4. Domains for 1zmt:
  1. Domain d1zmta1: 1zmt A:2-253 [125363]
    automatically matched to d1pwxa_
    complexed with rno
  2. Domain d1zmtb1: 1zmt B:2-253 [125364]
    automatically matched to d1pwxa_
    complexed with rno
  3. Domain d1zmtc1: 1zmt C:2-253 [125365]
    automatically matched to d1pwxa_
    complexed with rno
  4. Domain d1zmtd1: 1zmt D:2-253 [125366]
    automatically matched to d1pwxa_
    complexed with rno
5. Domains for 1zo8:
  1. Domain d1zo8a1: 1zo8 A:2-253 [125418]
    automatically matched to d1pwxa_
    complexed with sno
  2. Domain d1zo8b1: 1zo8 B:2-253 [125419]
    automatically matched to d1pwxa_
    complexed with sno
  3. Domain d1zo8c1: 1zo8 C:2-253 [125420]
    automatically matched to d1pwxa_
    complexed with sno
  4. Domain d1zo8d1: 1zo8 D:2-253 [125421]
    automatically matched to d1pwxa_
    complexed with sno
  5. Domain d1zo8e1: 1zo8 E:2-253 [125422]
    automatically matched to d1pwxa_
    complexed with sno
  6. Domain d1zo8f1: 1zo8 F:2-253 [125423]
    automatically matched to d1pwxa_
    complexed with sno
  7. Domain d1zo8g1: 1zo8 G:2-253 [125424]
    automatically matched to d1pwxa_
    complexed with sno
  8. Domain d1zo8h1: 1zo8 H:2-253 [125425]
    automatically matched to d1pwxa_
    complexed with sno
  9. Domain d1zo8i1: 1zo8 I:2-253 [125426]
    automatically matched to d1pwxa_
    complexed with sno
  10. Domain d1zo8j1: 1zo8 J:2-253 [125427]
    automatically matched to d1pwxa_
    complexed with sno
  11. Domain d1zo8k1: 1zo8 K:2-253 [125428]
    automatically matched to d1pwxa_
    complexed with sno
  12. Domain d1zo8l1: 1zo8 L:2-253 [125429]
    automatically matched to d1pwxa_
    complexed with sno
  13. Domain d1zo8m1: 1zo8 M:2-253 [125430]
    automatically matched to d1pwxa_
    complexed with sno
  14. Domain d1zo8n1: 1zo8 N:2-253 [125431]
    automatically matched to d1pwxa_
    complexed with sno
  15. Domain d1zo8o1: 1zo8 O:2-253 [125432]
    automatically matched to d1pwxa_
    complexed with sno
  16. Domain d1zo8p1: 1zo8 P:2-253 [125433]
    automatically matched to d1pwxa_
    complexed with sno

More info for Protein Halohydrin dehalogenase HheC from c.2.1.2: Tyrosine-dependent oxidoreductases

Timeline for Protein Halohydrin dehalogenase HheC from c.2.1.2: Tyrosine-dependent oxidoreductases:

Protein Halohydrin dehalogenase HheC from c.2.1.2: Tyrosine-dependent oxidoreductases first appeared in SCOP 1.67
Protein Halohydrin dehalogenase HheC from c.2.1.2: Tyrosine-dependent oxidoreductases appears in SCOP 1.71
Protein Halohydrin dehalogenase HheC from c.2.1.2: Tyrosine-dependent oxidoreductases appears in SCOP 1.75
Protein Halohydrin dehalogenase HheC from c.2.1.2: Tyrosine-dependent oxidoreductases appears in the current release, SCOPe 2.08