Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily) core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456 The nucleotide-binding modes of this and the next two folds/superfamilies are similar |
Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) |
Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins) also known as short-chain dehydrogenases and SDR family parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7 has additional subdomain(s) that are not in the common domain |
Protein Type II 3-hydroxyacyl-CoA dehydrogenase [63933] (3 species) |
Species Human (Homo sapiens) [TaxId:9606] [102152] (2 PDB entries) Uniprot Q99714 |
Domain d1so8a_: 1so8 A: [98940] complexed with cl, na |
Domain d1u7ta_: 1u7t A: [113099] complexed with nad, tdt |
Domain d1u7tb_: 1u7t B: [113100] complexed with nad, tdt |
Domain d1u7tc_: 1u7t C: [113101] complexed with nad, tdt |
Domain d1u7td_: 1u7t D: [113102] complexed with nad, tdt |
Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.2.1.2 Type II 3-hydroxyacyl-CoA dehydrogenase: