Lineage for Species: Trypanosoma cruzi [TaxId: 5693]

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 685975Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 685976Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families) (S)
  5. 686289Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (70 proteins)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 686542Protein Dihydropteridin reductase (pteridine reductase) [51769] (6 species)
  7. 686594Species Trypanosoma cruzi [TaxId:5693] [102146] (2 PDB entries)

PDB entries in Species: Trypanosoma cruzi [TaxId: 5693]:

  1. Domain(s) for 1mxf:
    1. 686599Domain d1mxfa_: 1mxf A: [91486]
    2. 686600Domain d1mxfb_: 1mxf B: [91487]
    3. 686601Domain d1mxfc_: 1mxf C: [91488]
    4. 686602Domain d1mxfd_: 1mxf D: [91489]
      complexed with mtx, ndp
  2. Domain(s) for 1mxh:
    1. 686595Domain d1mxha_: 1mxh A: [91490]
    2. 686596Domain d1mxhb_: 1mxh B: [91491]
    3. 686597Domain d1mxhc_: 1mxh C: [91492]
    4. 686598Domain d1mxhd_: 1mxh D: [91493]
      complexed with dhf, nap

More info for Species Trypanosoma cruzi [TaxId:5693] from c.2.1.2 Dihydropteridin reductase (pteridine reductase)

Timeline for Species Trypanosoma cruzi [TaxId:5693] from c.2.1.2 Dihydropteridin reductase (pteridine reductase):