Class c: Alpha and beta proteins (a/b) [51349] (130 folds) |
Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily) core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456 The nucleotide-binding modes of this and the next two folds/superfamilies are similar |
Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (11 families) |
Family c.2.1.1: Alcohol dehydrogenase-like, C-terminal domain [51736] (12 proteins) N-terminal all-beta domain defines family |
Protein Ketose reductase (sorbitol dehydrogenase) [51745] (2 species) |
Species Human (Homo sapiens) [TaxId:9606] [102130] (3 PDB entries) |
Domain d1pl6a2: 1pl6 A:146-316 [94863] Other proteins in same PDB: d1pl6a1, d1pl6b1, d1pl6c1, d1pl6d1 |
Domain d1pl6b2: 1pl6 B:146-316 [94865] Other proteins in same PDB: d1pl6a1, d1pl6b1, d1pl6c1, d1pl6d1 |
Domain d1pl6c2: 1pl6 C:146-316 [94867] Other proteins in same PDB: d1pl6a1, d1pl6b1, d1pl6c1, d1pl6d1 |
Domain d1pl6d2: 1pl6 D:146-316 [94869] Other proteins in same PDB: d1pl6a1, d1pl6b1, d1pl6c1, d1pl6d1 complexed with 572, nad, zn |
Domain d1pl7a2: 1pl7 A:146-316 [94871] Other proteins in same PDB: d1pl7a1, d1pl7b1, d1pl7c1, d1pl7d1 |
Domain d1pl7b2: 1pl7 B:146-316 [94873] Other proteins in same PDB: d1pl7a1, d1pl7b1, d1pl7c1, d1pl7d1 |
Domain d1pl7c2: 1pl7 C:146-316 [94875] Other proteins in same PDB: d1pl7a1, d1pl7b1, d1pl7c1, d1pl7d1 |
Domain d1pl7d2: 1pl7 D:146-316 [94877] Other proteins in same PDB: d1pl7a1, d1pl7b1, d1pl7c1, d1pl7d1 complexed with zn |
Domain d1pl8a2: 1pl8 A:146-316 [94879] Other proteins in same PDB: d1pl8a1, d1pl8b1, d1pl8c1, d1pl8d1 |
Domain d1pl8b2: 1pl8 B:146-316 [94881] Other proteins in same PDB: d1pl8a1, d1pl8b1, d1pl8c1, d1pl8d1 |
Domain d1pl8c2: 1pl8 C:146-316 [94883] Other proteins in same PDB: d1pl8a1, d1pl8b1, d1pl8c1, d1pl8d1 |
Domain d1pl8d2: 1pl8 D:146-316 [94885] Other proteins in same PDB: d1pl8a1, d1pl8b1, d1pl8c1, d1pl8d1 complexed with nad, zn |
Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.2.1.1 Ketose reductase (sorbitol dehydrogenase):