SCOP 1.69: Superfamily c.1.28: Radical SAM enzymes

Lineage for Superfamily c.1.28: Radical SAM enzymes

1. Root: SCOP 1.69

2. Class c: Alpha and beta proteins (a/b) [51349] (136 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (31 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.28: Radical SAM enzymes [102114] (3 families)
   common Fe-S cluster and SAM binding sites are embedded into complete or incomplete beta/alpha-barrel

Families:

1. c.1.28.1: Biotin synthase [102115] (1 protein)
   regular (beta/alpha)8 barrel

2. c.1.28.2: Oxygen-independent coproporphyrinogen III oxidase HemN [102118] (1 protein)
   open beta/alpha barrel decorated with additional structures

3. c.1.28.3: MoCo biosynthesis proteins [110388] (1 protein)
   open alpha/beta-barrel with a specific second FeS cluster-binding region corresponding to Pfam 06463

More info for Superfamily c.1.28: Radical SAM enzymes

Timeline for Superfamily c.1.28: Radical SAM enzymes:

• Superfamily c.1.28: Radical SAM enzymes first appeared in SCOP 1.67
  
• Superfamily c.1.28: Radical SAM enzymes appears in SCOP 1.71
  
• Superfamily c.1.28: Radical SAM enzymes appears in the current release, SCOPe 2.08