Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2078560Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2080913Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families) (S)
  5. 2080914Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 protein domains)
    Common fold covers whole protein structure
  6. 2081137Protein Prostaglandin d2 11-ketoreductase (akr1c3) [102051] (1 species)
    Aldo-keto reductase family 1 member c3
  7. 2081138Species Human (Homo sapiens) [TaxId:9606] [102052] (43 PDB entries)
    Uniprot P42330

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1ry0:
    1. 2081153Domain d1ry0a_: 1ry0 A: [111963]
      complexed with nap, pg2
    2. 2081154Domain d1ry0b_: 1ry0 B: [111964]
      complexed with nap, pg2
  2. Domain(s) for 1ry8:
    1. 2081151Domain d1ry8a_: 1ry8 A: [111965]
      complexed with ndp, rut
    2. 2081152Domain d1ry8b_: 1ry8 B: [111966]
      complexed with ndp, rut
  3. Domain(s) for 1s1p:
  4. Domain(s) for 1s1r:
  5. Domain(s) for 1s2a:
  6. Domain(s) for 1s2c:
  7. Domain(s) for 1xf0:
  8. Domain(s) for 1zq5:
  9. Domain(s) for 2f38:
  10. Domain(s) for 2fgb:
  11. Domain(s) for 3r43:
  12. Domain(s) for 3r58:
  13. Domain(s) for 3r6i:
  14. Domain(s) for 3r7m:
  15. Domain(s) for 3r8g:
  16. Domain(s) for 3r8h:
  17. Domain(s) for 3r94:
  18. Domain(s) for 3ufy:
  19. Domain(s) for 3ug8:
  20. Domain(s) for 3ugr:
  21. Domain(s) for 3uwe:
  22. Domain(s) for 4dbs:
    1. 2081148Domain d4dbsa_: 4dbs A: [219666]
      automated match to d1xf0a_
      complexed with 0hv, nap
    2. 2081149Domain d4dbsb_: 4dbs B: [219667]
      automated match to d1xf0a_
      complexed with 0hv, nap
  23. Domain(s) for 4dbu:
    1. 2081182Domain d4dbua_: 4dbu A: [219668]
      automated match to d1xf0a_
      complexed with bt9, nap
    2. 2081183Domain d4dbub_: 4dbu B: [219669]
      automated match to d1xf0a_
      complexed with bt9, nap
  24. Domain(s) for 4dbw:
    1. 2081145Domain d4dbwa_: 4dbw A: [193938]
      automated match to d2fgba_
      complexed with 511, nap
    2. 2081146Domain d4dbwb_: 4dbw B: [193937]
      automated match to d2fgba_
      complexed with 511, nap
  25. Domain(s) for 4dz5:
  26. Domain(s) for 4fa3:
  27. Domain(s) for 4fal:
  28. Domain(s) for 4fam:
    1. 2081158Domain d4fama_: 4fam A: [221100]
      automated match to d4h7ca_
      complexed with 0sz, edo, nap
    2. 2081159Domain d4famb_: 4fam B: [221101]
      automated match to d4h7ca_
      complexed with 0sz, edo, nap
  29. Domain(s) for 4h7c:
  30. Domain(s) for 4hmn:
  31. Domain(s) for 4wdt:
  32. Domain(s) for 4wdu:
  33. Domain(s) for 4wdw:
    1. 2081177Domain d4wdwa_: 4wdw A: [271537]
      automated match to d1s1pa_
      complexed with nap, wdw
    2. 2081178Domain d4wdwb_: 4wdw B: [271534]
      automated match to d1s1pa_
      complexed with nap, wdw
  34. Domain(s) for 4wdx:
    1. 2081167Domain d4wdxa_: 4wdx A: [271538]
      automated match to d1s1pa_
      complexed with nap, wdx
    2. 2081168Domain d4wdxb_: 4wdx B: [271539]
      automated match to d1s1pa_
      complexed with nap, wdx
  35. Domain(s) for 4wrh:
  36. Domain(s) for 4xvd:
    1. 2081189Domain d4xvda_: 4xvd A: [271582]
      automated match to d2fgba_
      complexed with nap, wdv
    2. 2081190Domain d4xvdb_: 4xvd B: [271585]
      automated match to d2fgba_
      complexed with nap, wdv
  37. Domain(s) for 4xve:
  38. Domain(s) for 4yvv:
    1. 2081187Domain d4yvva_: 4yvv A: [279657]
      automated match to d2fgba_
      complexed with gbm, nap
    2. 2081188Domain d4yvvb_: 4yvv B: [279658]
      automated match to d2fgba_
      complexed with gbm, nap
  39. Domain(s) for 4yvx:
    1. 2081185Domain d4yvxa_: 4yvx A: [279661]
      automated match to d2fgba_
      complexed with gmr, nap
    2. 2081186Domain d4yvxb_: 4yvx B: [279659]
      automated match to d2fgba_
      complexed with gmr, nap
  40. Domain(s) for 4zfc:
    1. 2081179Domain d4zfca_: 4zfc A: [279669]
      automated match to d2fgba_
      complexed with gcz, nap
    2. 2081180Domain d4zfcb_: 4zfc B: [279670]
      automated match to d2fgba_
      complexed with gcz, nap
  41. Domain(s) for 5hnt:
    1. 2287677Domain d5hntc_: 5hnt C: [330978]
      automated match to d3uwea_
      complexed with nap, qap
    2. 2287729Domain d5hnta_: 5hnt A: [331030]
      automated match to d3uwea_
      complexed with nap, qap
  42. Domain(s) for 5hnu:
    1. 2285616Domain d5hnuc_: 5hnu C: [328917]
      automated match to d3uwea_
      complexed with 65d, nap
    2. 2285644Domain d5hnua_: 5hnu A: [328945]
      automated match to d3uwea_
      complexed with 65d, nap
  43. Domain(s) for 5jm5:
    1. 2290460Domain d5jm5b_: 5jm5 B: [333761]
      automated match to d2fgba_
      complexed with 6lg, 6ny, nap
    2. 2290541Domain d5jm5a_: 5jm5 A: [333842]
      automated match to d2fgba_
      complexed with 6lg, 6ny, nap

More info for Species Human (Homo sapiens) [TaxId:9606] from c.1.7.1 Prostaglandin d2 11-ketoreductase (akr1c3)

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.1.7.1 Prostaglandin d2 11-ketoreductase (akr1c3):