SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2042196Fold b.29: Concanavalin A-like lectins/glucanases [49898] (1 superfamily)
    sandwich; 12-14 strands in 2 sheets; complex topology
  4. 2042197Superfamily b.29.1: Concanavalin A-like lectins/glucanases [49899] (26 families) (S)
  5. 2043012Family b.29.1.3: Galectin (animal S-lectin) [49932] (9 protein domains)
  6. 2043029Protein Galectin-1 [100925] (5 species)
  7. 2043046Species Human (Homo sapiens) [TaxId:9606] [101638] (27 PDB entries)
    Uniprot P09382

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1gzw:
    1. 2043057Domain d1gzwa_: 1gzw A: [90535]
      complexed with bme, so4
    2. 2043058Domain d1gzwb_: 1gzw B: [90536]
      complexed with bme, so4
  2. Domain(s) for 1w6m:
    1. 2043079Domain d1w6ma_: 1w6m A: [114273]
      complexed with bme, gal, so4
    2. 2043080Domain d1w6mb_: 1w6m B: [114274]
      complexed with bme, gal, so4
  3. Domain(s) for 1w6n:
    1. 2043049Domain d1w6na_: 1w6n A: [114275]
      complexed with bme, so4
    2. 2043050Domain d1w6nb_: 1w6n B: [114276]
      complexed with bme, so4
  4. Domain(s) for 1w6o:
    1. 2043071Domain d1w6oa_: 1w6o A: [114277]
      complexed with bme, lat, so4
    2. 2043072Domain d1w6ob_: 1w6o B: [114278]
      complexed with bme, lat, so4
  5. Domain(s) for 1w6p:
    1. 2043063Domain d1w6pa_: 1w6p A: [114279]
      complexed with bme, so4
    2. 2043064Domain d1w6pb_: 1w6p B: [114280]
      complexed with bme, so4
  6. Domain(s) for 1w6q:
    1. 2043081Domain d1w6qa_: 1w6q A: [114281]
      complexed with bme
    2. 2043082Domain d1w6qb_: 1w6q B: [114282]
      complexed with bme
  7. Domain(s) for 2km2:
    1. 2043089Domain d2km2a_: 2km2 A: [242559]
      automated match to d1gzwa_
    2. 2043090Domain d2km2b_: 2km2 B: [242560]
      automated match to d1gzwa_
  8. Domain(s) for 2zkn:
    1. 2043073Domain d2zkna_: 2zkn A: [171287]
      automated match to d1gzwa_
      mutant
    2. 2043074Domain d2zknb_: 2zkn B: [171288]
      automated match to d1gzwa_
      mutant
  9. Domain(s) for 3oy8:
    1. 2043075Domain d3oy8a_: 3oy8 A: [183404]
      automated match to d1gzwa_
    2. 2043076Domain d3oy8b_: 3oy8 B: [183405]
      automated match to d1gzwa_
  10. Domain(s) for 3oyw:
    1. 2043077Domain d3oywa_: 3oyw A: [183406]
      automated match to d1gzwa_
      complexed with tdg
    2. 2043078Domain d3oywb_: 3oyw B: [183407]
      automated match to d1gzwa_
      complexed with tdg
  11. Domain(s) for 3t2t:
    1. 2043065Domain d3t2ta_: 3t2t A: [185620]
      automated match to d1gzwa_
      complexed with mqt
    2. 2043066Domain d3t2tb_: 3t2t B: [185621]
      automated match to d1gzwa_
      complexed with mqt
  12. Domain(s) for 3w58:
    1. 2043067Domain d3w58a_: 3w58 A: [236489]
      automated match to d1gzwa_
      complexed with bme, gol, so4
    2. 2043068Domain d3w58b_: 3w58 B: [236490]
      automated match to d1gzwa_
      complexed with bme, gol, so4
    3. 2043069Domain d3w58c_: 3w58 C: [236501]
      automated match to d1gzwa_
      complexed with bme, gol, so4
    4. 2043070Domain d3w58d_: 3w58 D: [236497]
      automated match to d1gzwa_
      complexed with bme, gol, so4
  13. Domain(s) for 3w59:
    1. 2043085Domain d3w59a_: 3w59 A: [236502]
      automated match to d1gzwa_
      complexed with bme, gol, so4
    2. 2043086Domain d3w59b_: 3w59 B: [236491]
      automated match to d1gzwa_
      complexed with bme, gol, so4
    3. 2043087Domain d3w59c_: 3w59 C: [236496]
      automated match to d1gzwa_
      complexed with bme, gol, so4
    4. 2043088Domain d3w59d_: 3w59 D: [236498]
      automated match to d1gzwa_
      complexed with bme, gol, so4
  14. Domain(s) for 4q1p:
    1. 2043059Domain d4q1pa_: 4q1p A: [277875]
      automated match to d1gzwa_
      complexed with 2xt, bme, so4
    2. 2043060Domain d4q1pb_: 4q1p B: [277879]
      automated match to d1gzwa_
      complexed with 2xt, bme, so4
  15. Domain(s) for 4q1r:
    1. 2043061Domain d4q1ra_: 4q1r A: [277874]
      automated match to d1gzwa_
      complexed with 2xu, so4
    2. 2043062Domain d4q1rb_: 4q1r B: [277876]
      automated match to d1gzwa_
      complexed with 2xu, so4
  16. Domain(s) for 4q26:
    1. 2043053Domain d4q26a_: 4q26 A: [277880]
      automated match to d1gzwa_
      complexed with gol, nlc
    2. 2043054Domain d4q26b_: 4q26 B: [277881]
      automated match to d1gzwa_
      complexed with gol, nlc
    3. 2043055Domain d4q26g_: 4q26 G: [277882]
      automated match to d1gzwa_
      complexed with gol, nlc
    4. 2043056Domain d4q26h_: 4q26 H: [277884]
      automated match to d1gzwa_
      complexed with gol, nlc
  17. Domain(s) for 4q27:
    1. 2043047Domain d4q27a_: 4q27 A: [277878]
      automated match to d1gzwa_
      complexed with 2xv, so4
    2. 2043048Domain d4q27b_: 4q27 B: [277877]
      automated match to d1gzwa_
      complexed with 2xv, so4
  18. Domain(s) for 4q2f:
    1. 2043051Domain d4q2fa_: 4q2f A: [277883]
      automated match to d1gzwa_
      complexed with 2xw, so4
    2. 2043052Domain d4q2fb_: 4q2f B: [277885]
      automated match to d1gzwa_
      complexed with 2xw, so4
  19. Domain(s) for 4xbl:
    1. 2043083Domain d4xbla_: 4xbl A: [273030]
      automated match to d1gzwa_
      complexed with gal, nag
    2. 2043084Domain d4xblb_: 4xbl B: [273029]
      automated match to d1gzwa_
      complexed with gal, nag
  20. Domain(s) for 4y1u:
    1. 2268488Domain d4y1ua_: 4y1u A: [311794]
      automated match to d4q27b_
      complexed with gal, mag
    2. 2268581Domain d4y1ub_: 4y1u B: [311887]
      automated match to d4q27b_
      complexed with gal, mag
  21. Domain(s) for 4y1v:
    1. 2268552Domain d4y1vb_: 4y1v B: [311858]
      automated match to d4q27b_
      complexed with gal, mag
    2. 2268671Domain d4y1va_: 4y1v A: [311977]
      automated match to d4q27b_
      complexed with gal, mag
  22. Domain(s) for 4y1x:
    1. 2268479Domain d4y1xb_: 4y1x B: [311785]
      automated match to d4q27b_
      complexed with 6s2, gal
    2. 2268556Domain d4y1xa_: 4y1x A: [311862]
      automated match to d4q27b_
      complexed with 6s2, gal
  23. Domain(s) for 4y1y:
    1. 2269065Domain d4y1ya_: 4y1y A: [312371]
      automated match to d3w59a_
      complexed with 6s2, gal
    2. 2269704Domain d4y1yb_: 4y1y B: [313009]
      automated match to d3w59a_
      complexed with 6s2, gal
  24. Domain(s) for 4y1z:
    1. 2268455Domain d4y1zb_: 4y1z B: [311761]
      automated match to d4q27b_
      complexed with 6c2, gal
    2. 2268487Domain d4y1za_: 4y1z A: [311793]
      automated match to d4q27b_
      complexed with 6c2, gal
  25. Domain(s) for 4y20:
    1. 2268459Domain d4y20a_: 4y20 A: [311765]
      automated match to d4q27b_
      complexed with slt
    2. 2268591Domain d4y20b_: 4y20 B: [311897]
      automated match to d4q27b_
      complexed with slt
  26. Domain(s) for 4y22:
    1. 2268608Domain d4y22a_: 4y22 A: [311914]
      automated match to d4q27b_
      complexed with mag, sga
    2. 2268616Domain d4y22b_: 4y22 B: [311922]
      automated match to d4q27b_
      complexed with mag, sga
  27. Domain(s) for 4y24:
    1. 2273062Domain d4y24b_: 4y24 B: [316363]
      automated match to d4q27b_
      complexed with td2
    2. 2273064Domain d4y24a_: 4y24 A: [316365]
      automated match to d4q27b_
      complexed with td2

More info for Species Human (Homo sapiens) [TaxId:9606] from b.29.1.3 Galectin-1

Timeline for Species Human (Homo sapiens) [TaxId:9606] from b.29.1.3 Galectin-1: