SCOPe 2.03: Protein: Synaptotagmin IV

Root: SCOPe 2.03
Class b: All beta proteins [48724] (174 folds)
Fold b.7: C2 domain-like [49561] (5 superfamilies)
sandwich; 8 strands in 2 sheets; greek-key
Superfamily b.7.1: C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (3 families)
two constituent families are related by circular permutation
Family b.7.1.2: Synaptotagmin-like (S variant) [49575] (11 proteins)
topologically similar to the C-terminal domain of PapD
Protein Synaptotagmin IV [101562] (2 species)
duplication: contains 2 C2 domains

Human (Homo sapiens) [TaxId:9606] [101563] (1 PDB entry)
- Domain for 1ugk:
  - Domain d1ugka_: 1ugk A: [99365]
Norway rat (Rattus norvegicus) [TaxId:10116] [110115] (2 PDB entries)
Uniprot P50232 288-425
1. Domain for 1w15:
  - Domain d1w15a_: 1w15 A: [109041]
    second C2 domain
    complexed with ca, cl, na
2. Domain for 1w16:
  - Domain d1w16a_: 1w16 A: [109042]
    second C2 domain
    complexed with cl, na

Timeline for Protein Synaptotagmin IV from b.7.1.2: Synaptotagmin-like (S variant):

Protein Synaptotagmin IV from b.7.1.2: Synaptotagmin-like (S variant) first appeared in SCOP 1.67
Protein Synaptotagmin IV from b.7.1.2: Synaptotagmin-like (S variant) appears in SCOPe 2.02
Protein Synaptotagmin IV from b.7.1.2: Synaptotagmin-like (S variant) appears in SCOPe 2.04
Protein Synaptotagmin IV from b.7.1.2: Synaptotagmin-like (S variant) appears in the current release, SCOPe 2.08