Lineage for Species: Human (Homo sapiens), cluster 4 [TaxId: 9606]

  1. Root: SCOPe 2.03
  2. 1287432Class b: All beta proteins [48724] (174 folds)
  3. 1287433Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 1287434Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 1287435Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 1287638Protein Immunoglobulin heavy chain variable domain, VH [88543] (21 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 1287888Species Human (Homo sapiens), cluster 4 [TaxId:9606] [101505] (4 PDB entries)

PDB entries in Species: Human (Homo sapiens), cluster 4 [TaxId: 9606]:

  1. Domain(s) for 1q1j:
    1. 1287893Domain d1q1jh1: 1q1j H:1-113 [95581]
      Other proteins in same PDB: d1q1jh2, d1q1ji2, d1q1jl1, d1q1jl2, d1q1jm1, d1q1jm2
      part of anti HIV-1 Fab 447-52d
    2. 1287894Domain d1q1ji1: 1q1j I:1-113 [95583]
      Other proteins in same PDB: d1q1jh2, d1q1ji2, d1q1jl1, d1q1jl2, d1q1jm1, d1q1jm2
      part of anti HIV-1 Fab 447-52d
  2. Domain(s) for 2b4c:
  3. Domain(s) for 3c2a:
    1. 1287891Domain d3c2ah1: 3c2a H:1-113 [155872]
      Other proteins in same PDB: d3c2ah2, d3c2ai2
      automatically matched to d1q1jh1
    2. 1287892Domain d3c2ai1: 3c2a I:1-113 [155874]
      Other proteins in same PDB: d3c2ah2, d3c2ai2
      automatically matched to d1q1jh1
  4. Domain(s) for 4m1d:
    1. 1287889Domain d4m1dh1: 4m1d H:1-113 [227791]
      Other proteins in same PDB: d4m1dh2, d4m1di2, d4m1dm1, d4m1dm2
      automated match to d1q1jh1
      complexed with gol
    2. 1287890Domain d4m1di1: 4m1d I:1-113 [227793]
      Other proteins in same PDB: d4m1dh2, d4m1di2, d4m1dm1, d4m1dm2
      automated match to d1q1jh1
      complexed with gol

More info for Species Human (Homo sapiens), cluster 4 [TaxId:9606] from b.1.1.1 Immunoglobulin heavy chain variable domain, VH

Timeline for Species Human (Homo sapiens), cluster 4 [TaxId:9606] from b.1.1.1 Immunoglobulin heavy chain variable domain, VH: