![]() | Class a: All alpha proteins [46456] (284 folds) |
![]() | Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily) multihelical; consists of two different alpha-helical bundles |
![]() | Superfamily a.211.1: HD-domain/PDEase-like [109604] (5 families) ![]() |
![]() | Family a.211.1.2: PDEase [48548] (6 proteins) Pfam PF00233; multihelical; can be divided into three subdomains |
![]() | Protein cGMP-specific 3',5'-cyclic phosphodiesterase pde5a1-Ibmx [101439] (1 species) |
![]() | Human (Homo sapiens) [TaxId:9606] [101440] (15 PDB entries) Uniprot O76074 534-860 |
![]() | Domain d1rkpa_: 1rkp A: [97620] complexed with ibm, mg, zn; mutant |
![]() | Domain d1t9ra_: 1t9r A: [106725] complexed with cit, po4, zn |
![]() | Domain d1t9sa_: 1t9s A: [106726] |
![]() | Domain d1t9sb_: 1t9s B: [106727] complexed with 5gp, mg, zn |
![]() | Domain d1tbfa_: 1tbf A: [106743] complexed with gol, mg, via, zn |
![]() | Domain d1udta_: 1udt A: [99221] complexed with mg, via, zn |
![]() | Domain d1udua_: 1udu A: [99222] |
![]() | Domain d1udub_: 1udu B: [99223] complexed with cia, mg, zn |
![]() | Domain d1uhoa_: 1uho A: [107851] complexed with mg, vdn, zn |
![]() | Domain d1xoza_: 1xoz A: [115719] complexed with cia, mg, zn |
![]() | Domain d1xp0a_: 1xp0 A: [115720] complexed with mg, vdn, zn |
![]() | Domain d2chma1: 2chm A:537-858 [130472] complexed with 3p4, mes, mg, zn |
![]() | Domain d2h40a1: 2h40 A:535-860 [136063] automatically matched to d1t9ra_ complexed with mg, zn |
![]() | Domain d2h42a1: 2h42 A:535-860 [136064] automatically matched to d1t9ra_ complexed with mg, via, zn |
![]() | Domain d2h42b1: 2h42 B:535-860 [136065] automatically matched to d1t9ra_ complexed with mg, via, zn |
![]() | Domain d2h42c1: 2h42 C:535-860 [136066] automatically matched to d1t9ra_ complexed with mg, via, zn |
![]() | Domain d2h44a1: 2h44 A:535-860 [136069] automatically matched to d1t9ra_ complexed with 7ca, mg, zn |
![]() | Domain d3b2ra1: 3b2r A:535-860 [154768] automatically matched to d1t9ra_ complexed with vdn |
![]() | Domain d3b2rb1: 3b2r B:538-860 [154769] automatically matched to d1t9ra_ complexed with vdn |
![]() | Domain d3bjca1: 3bjc A:535-860 [155329] automatically matched to d1t9ra_ complexed with mg, wan, zn |
Timeline for Protein cGMP-specific 3',5'-cyclic phosphodiesterase pde5a1-Ibmx from a.211.1.2: PDEase: