Lineage for Protein: Hydroxyisobutyrate dehydrogenase

  1. Root: SCOP 1.73
  2. 631650Class a: All alpha proteins [46456] (258 folds)
  3. 645590Fold a.100: 6-phosphogluconate dehydrogenase C-terminal domain-like [48178] (1 superfamily)
    multihelical; common core is formed around two long antiparallel helices related by (pseudo) twofold symmetry
  4. 645591Superfamily a.100.1: 6-phosphogluconate dehydrogenase C-terminal domain-like [48179] (12 families) (S)
    N-terminal domain is Rossmann-fold with a family-specific C-terminal extension
  5. 645592Family a.100.1.1: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain [48180] (2 proteins)
    Hydroxyisobutyrate dehydrogenase domain is similar to one structural repeat in the 6-phosphogluconate dehydrogenase domain
  6. 645603Protein Hydroxyisobutyrate dehydrogenase [101357] (2 species)
    forms similar dimeric and tetrameric structures to the 6-phosphogluconate dehydrogenase domain and its dimer, respectively

Species:

  1. 645604Salmonella typhimurium [TaxId:90371] [109948] (1 PDB entry)
  2. 645606Thermus thermophilus [TaxId:274] [101358] (2 PDB entries)
    structural genomics
    1. Domains for 1wp4:
      1. 645611Domain d1wp4a1: 1wp4 A:158-289 [121135]
        Other proteins in same PDB: d1wp4a2, d1wp4b2, d1wp4c2, d1wp4d2
        automatically matched to d1j3va1
        complexed with ndp, so4
      2. 645612Domain d1wp4b1: 1wp4 B:158-289 [121137]
        Other proteins in same PDB: d1wp4a2, d1wp4b2, d1wp4c2, d1wp4d2
        automatically matched to d1j3va1
        complexed with ndp, so4
      3. 645613Domain d1wp4c1: 1wp4 C:158-289 [121139]
        Other proteins in same PDB: d1wp4a2, d1wp4b2, d1wp4c2, d1wp4d2
        automatically matched to d1j3va1
        complexed with ndp, so4
      4. 645614Domain d1wp4d1: 1wp4 D:158-289 [121141]
        Other proteins in same PDB: d1wp4a2, d1wp4b2, d1wp4c2, d1wp4d2
        automatically matched to d1j3va1
        complexed with ndp, so4
    2. Domains for 2cvz:
      1. 645607Domain d2cvza1: 2cvz A:158-289 [130890]
        Other proteins in same PDB: d2cvza2, d2cvzb2, d2cvzc2, d2cvzd2
        automatically matched to d1j3va1
        complexed with ndp
      2. 645608Domain d2cvzb1: 2cvz B:158-289 [130892]
        Other proteins in same PDB: d2cvza2, d2cvzb2, d2cvzc2, d2cvzd2
        automatically matched to d1j3va1
        complexed with ndp
      3. 645609Domain d2cvzc1: 2cvz C:158-289 [130894]
        Other proteins in same PDB: d2cvza2, d2cvzb2, d2cvzc2, d2cvzd2
        automatically matched to d1j3va1
        complexed with ndp
      4. 645610Domain d2cvzd1: 2cvz D:158-289 [130896]
        Other proteins in same PDB: d2cvza2, d2cvzb2, d2cvzc2, d2cvzd2
        automatically matched to d1j3va1
        complexed with ndp

More info for Protein Hydroxyisobutyrate dehydrogenase from a.100.1.1: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain

Timeline for Protein Hydroxyisobutyrate dehydrogenase from a.100.1.1: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain:

  • Protein Hydroxyisobutyrate dehydrogenase from a.100.1.1: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain first appeared in SCOP 1.67
  • Protein Hydroxyisobutyrate dehydrogenase from a.100.1.1: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain appears in SCOP 1.71
  • Protein Hydroxyisobutyrate dehydrogenase from a.100.1.1: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain appears in SCOP 1.75
  • Protein Hydroxyisobutyrate dehydrogenase from a.100.1.1: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain appears in the current release, SCOPe 2.07