Lineage for Protein: Hydroxyisobutyrate dehydrogenase
- Root: SCOP 1.71
Class a: All alpha proteins [46456] (226 folds) 
Fold a.100: 6-phosphogluconate dehydrogenase C-terminal domain-like [48178] (1 superfamily)
multihelical; common core is formed around two long antiparallel helices related by (pseudo) twofold symmetrySuperfamily a.100.1: 6-phosphogluconate dehydrogenase C-terminal domain-like [48179] (10 families) 
N-terminal domain is Rossmann-fold with a family-specific C-terminal extensionFamily a.100.1.1: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain [48180] (2 proteins)
Hydroxyisobutyrate dehydrogenase domain is similar to one structural repeat in the 6-phosphogluconate dehydrogenase domainProtein Hydroxyisobutyrate dehydrogenase [101357] (2 species)
forms similar dimeric and tetrameric structures to the 6-phosphogluconate dehydrogenase domain and its dimer, respectively
Species:
Salmonella typhimurium [TaxId:90371] [109948] (1 PDB entry) - Domain for 1vpd:
Domain d1vpda1: 1vpd A:164-296 [113951]
Other proteins in same PDB: d1vpda2
Structural genomics target
complexed with cl, tla
- Domain for 1vpd:
Thermus thermophilus [TaxId:274] [101358] (1 PDB entry) - Domains for 1j3v:
Domain d1j3va1: 1j3v A:158-289 [90825]
Other proteins in same PDB: d1j3va2, d1j3vb2, d1j3vc2, d1j3vd2
Domain d1j3vb1: 1j3v B:158-289 [90827]
Other proteins in same PDB: d1j3va2, d1j3vb2, d1j3vc2, d1j3vd2
Domain d1j3vc1: 1j3v C:158-289 [90829]
Other proteins in same PDB: d1j3va2, d1j3vb2, d1j3vc2, d1j3vd2
Domain d1j3vd1: 1j3v D:158-289 [90831]
Other proteins in same PDB: d1j3va2, d1j3vb2, d1j3vc2, d1j3vd2
structural genomics
complexed with ndp
- Domains for 1j3v:
More info for Protein Hydroxyisobutyrate dehydrogenase from a.100.1.1: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain
Timeline for Protein Hydroxyisobutyrate dehydrogenase from a.100.1.1: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain:
- Protein Hydroxyisobutyrate dehydrogenase from a.100.1.1: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain first appeared in SCOP 1.67
- Protein Hydroxyisobutyrate dehydrogenase from a.100.1.1: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain appears in SCOP 1.69
- Protein Hydroxyisobutyrate dehydrogenase from a.100.1.1: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain appears in SCOP 1.73
- Protein Hydroxyisobutyrate dehydrogenase from a.100.1.1: Hydroxyisobutyrate and 6-phosphogluconate dehydrogenase domain appears in the current release, SCOPe 2.08