SCOPe 2.03: Family a.77.1.5: Pyrin domain, PYD

Lineage for Family a.77.1.5: Pyrin domain, PYD

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.77: DEATH domain [47985] (1 superfamily)
   6 helices: closed bundle; greek-key; internal pseudo twofold symmetry

4. Superfamily a.77.1: DEATH domain [47986] (4 families)

5. Family a.77.1.5: Pyrin domain, PYD [101298] (2 proteins)
   automatically mapped to Pfam PF02758

Proteins:

1. Apoptosis-associated speck-like protein Asc [101299] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [101300] (1 PDB entry)

2. NALP1 [101301] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [101302] (1 PDB entry)

More info for Family a.77.1.5: Pyrin domain, PYD

Timeline for Family a.77.1.5: Pyrin domain, PYD:

• Family a.77.1.5: Pyrin domain, PYD first appeared in SCOP 1.67
  
• Family a.77.1.5: Pyrin domain, PYD appears in SCOPe 2.02
  
• Family a.77.1.5: Pyrin domain, PYD appears in SCOPe 2.04
  
• Family a.77.1.5: Pyrin domain, PYD appears in the current release, SCOPe 2.08