SCOPe 2.08: Protein: DNA polymerase lambda

Lineage for Protein: DNA polymerase lambda

Root: SCOPe 2.08
Class a: All alpha proteins [46456] (290 folds)
Fold a.60: SAM domain-like [47768] (17 superfamilies)
4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins
Superfamily a.60.12: PsbU/PolX domain-like [81585] (3 families)
contains one classic and one pseudo HhH motifs
Family a.60.12.1: DNA polymerase beta-like, second domain [81584] (3 proteins)
topological similarity to the N-terminal domain
automatically mapped to Pfam PF10391
Protein DNA polymerase lambda [101253] (1 species)

Species:

Human (Homo sapiens) [TaxId:9606] [101254] (27 PDB entries)

Domains for 1rzt:
1. Domain d1rzta2: 1rzt A:329-385 [98225]
  Other proteins in same PDB: d1rzta1, d1rzta3, d1rzte1, d1rzte3, d1rzti1, d1rzti3, d1rztm1, d1rztm3
  protein/DNA complex; complexed with edo, na
2. Domain d1rzte2: 1rzt E:329-385 [98228]
  Other proteins in same PDB: d1rzta1, d1rzta3, d1rzte1, d1rzte3, d1rzti1, d1rzti3, d1rztm1, d1rztm3
  protein/DNA complex; complexed with edo, na
3. Domain d1rzti2: 1rzt I:329-385 [98231]
  Other proteins in same PDB: d1rzta1, d1rzta3, d1rzte1, d1rzte3, d1rzti1, d1rzti3, d1rztm1, d1rztm3
  protein/DNA complex; complexed with edo, na
4. Domain d1rztm2: 1rzt M:329-385 [98234]
  Other proteins in same PDB: d1rzta1, d1rzta3, d1rzte1, d1rzte3, d1rzti1, d1rzti3, d1rztm1, d1rztm3
  protein/DNA complex; complexed with edo, na

Domains for 1xsl:

Domain d1xsla2: 1xsl A:329-385 [122271]
Other proteins in same PDB: d1xsla1, d1xsla3, d1xsle1, d1xsle3, d1xsli1, d1xsli3, d1xslm1, d1xslm3
automatically matched to d1rzta2
protein/DNA complex; complexed with cac, mg, na

Domain d1xsle2: 1xsl E:329-385 [122274]
Other proteins in same PDB: d1xsla1, d1xsla3, d1xsle1, d1xsle3, d1xsli1, d1xsli3, d1xslm1, d1xslm3
automatically matched to d1rzta2
protein/DNA complex; complexed with cac, mg, na

Domain d1xsli2: 1xsl I:329-385 [122277]
Other proteins in same PDB: d1xsla1, d1xsla3, d1xsle1, d1xsle3, d1xsli1, d1xsli3, d1xslm1, d1xslm3
automatically matched to d1rzta2
protein/DNA complex; complexed with cac, mg, na

Domain d1xslm2: 1xsl M:329-385 [122280]
Other proteins in same PDB: d1xsla1, d1xsla3, d1xsle1, d1xsle3, d1xsli1, d1xsli3, d1xslm1, d1xslm3
automatically matched to d1rzta2
protein/DNA complex; complexed with cac, mg, na

Domain for 1xsn:
- Domain d1xsna2: 1xsn A:329-385 [122283]
  Other proteins in same PDB: d1xsna1, d1xsna3
  automatically matched to d1rzta2
  protein/DNA complex; complexed with d3t, edo, mg, na
Domain for 1xsp:
- Domain d1xspa2: 1xsp A:329-385 [122286]
  Other proteins in same PDB: d1xspa1, d1xspa3
  automatically matched to d1rzta2
  protein/DNA complex; complexed with na, ppv
Domain for 2bcq:
- Domain d2bcqa2: 2bcq A:329-385 [128305]
  Other proteins in same PDB: d2bcqa1, d2bcqa3
  automated match to d2bcqa2
  protein/DNA complex; complexed with edo, mg, na, ppv

Domains for 2gws:

Domain d2gwsa2: 2gws A:329-385 [135814]
Other proteins in same PDB: d2gwsa1, d2gwsa3, d2gwse1, d2gwse3, d2gwsi1, d2gwsi3, d2gwsm1, d2gwsm3
automated match to d2pfna2
protein/DNA complex; complexed with cac, cl, edo, mg, na

Domain d2gwse2: 2gws E:329-385 [135817]
Other proteins in same PDB: d2gwsa1, d2gwsa3, d2gwse1, d2gwse3, d2gwsi1, d2gwsi3, d2gwsm1, d2gwsm3
automated match to d2pfna2
protein/DNA complex; complexed with cac, cl, edo, mg, na

Domain d2gwsi2: 2gws I:329-385 [135820]
Other proteins in same PDB: d2gwsa1, d2gwsa3, d2gwse1, d2gwse3, d2gwsi1, d2gwsi3, d2gwsm1, d2gwsm3
automated match to d2pfna2
protein/DNA complex; complexed with cac, cl, edo, mg, na

Domain d2gwsm2: 2gws M:329-385 [135823]
Other proteins in same PDB: d2gwsa1, d2gwsa3, d2gwse1, d2gwse3, d2gwsi1, d2gwsi3, d2gwsm1, d2gwsm3
automated match to d2pfna2
protein/DNA complex; complexed with cac, cl, edo, mg, na

Domain for 2pfn:
- Domain d2pfna2: 2pfn A:329-385 [139673]
  Other proteins in same PDB: d2pfna1, d2pfna3
  automated match to d2pfna2
  protein/DNA complex; complexed with dup, mg, na
Domain for 2pfo:
- Domain d2pfoa2: 2pfo A:329-385 [139676]
  Other proteins in same PDB: d2pfoa1, d2pfoa3
  automated match to d2pfna2
  protein/DNA complex; complexed with dup, edo, mg, mn, na
Domain for 2pfp:
- Domain d2pfpa2: 2pfp A:329-385 [139679]
  Other proteins in same PDB: d2pfpa1, d2pfpa3
  automated match to d2pfna2
  protein/DNA complex; complexed with dcp, mg, na
Domain for 2pfq:
- Domain d2pfqa2: 2pfq A:329-385 [139682]
  Other proteins in same PDB: d2pfqa1, d2pfqa3
  automated match to d2pfna2
  protein/DNA complex; complexed with dcp, mg, mn, na, ppv
Domains for 3c5f:
1. Domain d3c5fa2: 3c5f A:329-385 [155938]
  Other proteins in same PDB: d3c5fa1, d3c5fa3, d3c5fb1, d3c5fb3
  automated match to d1xsna2
  protein/DNA complex; complexed with na; mutant
2. Domain d3c5fb2: 3c5f B:329-385 [155941]
  Other proteins in same PDB: d3c5fa1, d3c5fa3, d3c5fb1, d3c5fb3
  automated match to d1xsna2
  protein/DNA complex; complexed with na; mutant
Domains for 3c5g:
1. Domain d3c5ga2: 3c5g A:329-385 [155944]
  Other proteins in same PDB: d3c5ga1, d3c5ga3, d3c5gb1, d3c5gb3
  automated match to d1xsna2
  protein/DNA complex; complexed with d3t, edo, mg, na; mutant
2. Domain d3c5gb2: 3c5g B:329-385 [155947]
  Other proteins in same PDB: d3c5ga1, d3c5ga3, d3c5gb1, d3c5gb3
  automated match to d1xsna2
  protein/DNA complex; complexed with d3t, edo, mg, na; mutant
Domain for 3hw8:
- Domain d3hw8a2: 3hw8 A:329-385 [246599]
  Other proteins in same PDB: d3hw8a1, d3hw8a3
  automated match to d1xsna2
  protein/DNA complex; complexed with d3t, edo, mg, na
Domain for 3mdc:
- Domain d3mdca2: 3mdc A:329-385 [247642]
  Other proteins in same PDB: d3mdca1, d3mdca3
  automated match to d1xsna2
  protein/DNA complex; complexed with gtf, mg, na
Domains for 3mgh:
1. Domain d3mgha2: 3mgh A:329-385 [247695]
  Other proteins in same PDB: d3mgha1, d3mgha3, d3mghc1, d3mghc3
  automated match to d1xsna2
  protein/DNA complex; complexed with na; mutant
2. Domain d3mghc2: 3mgh C:329-385 [247698]
  Other proteins in same PDB: d3mgha1, d3mgha3, d3mghc1, d3mghc3
  automated match to d1xsna2
  protein/DNA complex; complexed with na; mutant
Domain for 3mgi:
- Domain d3mgia2: 3mgi A:329-385 [247701]
  Other proteins in same PDB: d3mgia1, d3mgia3
  automated match to d1xsna2
  protein/DNA complex; complexed with d3t, mg, na; mutant
Domains for 3pml:
1. Domain d3pmla2: 3pml A:329-385 [248522]
  Other proteins in same PDB: d3pmla1, d3pmla3, d3pmlb1, d3pmlb3
  automated match to d1xsna2
  protein/DNA complex; complexed with 1gc, mg, na
2. Domain d3pmlb2: 3pml B:329-385 [248525]
  Other proteins in same PDB: d3pmla1, d3pmla3, d3pmlb1, d3pmlb3
  automated match to d1xsna2
  protein/DNA complex; complexed with 1gc, mg, na
Domain for 3pmn:
- Domain d3pmna2: 3pmn A:329-385 [248528]
  Other proteins in same PDB: d3pmna1, d3pmna3
  automated match to d1xsna2
  protein/DNA complex; complexed with 1gc, cl, mg, mn, na
Domain for 3pnc:
- Domain d3pnca2: 3pnc A:329-385 [248541]
  Other proteins in same PDB: d3pnca1, d3pnca3
  automated match to d1xsna2
  protein/DNA complex; complexed with 1gc, mg, na, trs
Domain for 3upq:
- Domain d3upqa2: 3upq A:329-385 [250249]
  Other proteins in same PDB: d3upqa1, d3upqa3
  automated match to d1xsna2
  protein/DNA complex; complexed with mn, na, so4, zan
Domain for 3uq0:
- Domain d3uq0a2: 3uq0 A:329-385 [250253]
  Other proteins in same PDB: d3uq0a1, d3uq0a3
  automated match to d1xsna2
  protein/DNA complex; complexed with cl, edo, na, so4
Domain for 3uq1:
- Domain d3uq1a2: 3uq1 A:329-385 [306665]
  Other proteins in same PDB: d3uq1a1, d3uq1a3
  automated match to d2bcqa2
  protein/DNA complex; complexed with cl, f2a, mg, mn, na
Domain for 3uq2:
- Domain d3uq2a2: 3uq2 A:329-385 [250256]
  Other proteins in same PDB: d3uq2a1, d3uq2a3
  automated match to d1xsna2
  protein/DNA complex; complexed with mg, na, ppv
Domain for 4fo6:
- Domain d4fo6a2: 4fo6 A:329-385 [252041]
  Other proteins in same PDB: d4fo6a1, d4fo6a3
  automated match to d1xsna2
  protein/DNA complex; complexed with cl, f2a, mg, mn, na

Domains for 4k4g:

Domain d4k4ga2: 4k4g A:329-385 [257797]
Other proteins in same PDB: d4k4ga1, d4k4ga3, d4k4ga4, d4k4ge1, d4k4ge3, d4k4ge4, d4k4gi1, d4k4gi3, d4k4gi4, d4k4gm1, d4k4gm3, d4k4gm4
automated match to d1xsna2
protein/DNA complex; complexed with 1s0, act, ca, cac

Domain d4k4ge2: 4k4g E:329-385 [257794]
Other proteins in same PDB: d4k4ga1, d4k4ga3, d4k4ga4, d4k4ge1, d4k4ge3, d4k4ge4, d4k4gi1, d4k4gi3, d4k4gi4, d4k4gm1, d4k4gm3, d4k4gm4
automated match to d1xsna2
protein/DNA complex; complexed with 1s0, act, ca, cac

Domain d4k4gi2: 4k4g I:329-385 [262795]
Other proteins in same PDB: d4k4ga1, d4k4ga3, d4k4ga4, d4k4ge1, d4k4ge3, d4k4ge4, d4k4gi1, d4k4gi3, d4k4gi4, d4k4gm1, d4k4gm3, d4k4gm4
automated match to d2bcqa2
protein/DNA complex; complexed with 1s0, act, ca, cac

Domain d4k4gm2: 4k4g M:329-385 [262798]
Other proteins in same PDB: d4k4ga1, d4k4ga3, d4k4ga4, d4k4ge1, d4k4ge3, d4k4ge4, d4k4gi1, d4k4gi3, d4k4gi4, d4k4gm1, d4k4gm3, d4k4gm4
automated match to d2bcqa2
protein/DNA complex; complexed with 1s0, act, ca, cac

Domains for 4k4h:

Domain d4k4ha2: 4k4h A:329-385 [262801]
Other proteins in same PDB: d4k4ha1, d4k4ha3, d4k4ha4, d4k4he1, d4k4he3, d4k4he4, d4k4hi1, d4k4hi3, d4k4hi4, d4k4hm1, d4k4hm3, d4k4hm4
automated match to d2bcqa2
protein/DNA complex; complexed with 1rz, act, ca

Domain d4k4he2: 4k4h E:329-385 [258918]
Other proteins in same PDB: d4k4ha1, d4k4ha3, d4k4ha4, d4k4he1, d4k4he3, d4k4he4, d4k4hi1, d4k4hi3, d4k4hi4, d4k4hm1, d4k4hm3, d4k4hm4
automated match to d1xsna2
protein/DNA complex; complexed with 1rz, act, ca

Domain d4k4hi2: 4k4h I:329-385 [262804]
Other proteins in same PDB: d4k4ha1, d4k4ha3, d4k4ha4, d4k4he1, d4k4he3, d4k4he4, d4k4hi1, d4k4hi3, d4k4hi4, d4k4hm1, d4k4hm3, d4k4hm4
automated match to d2bcqa2
protein/DNA complex; complexed with 1rz, act, ca

Domain d4k4hm2: 4k4h M:329-385 [262807]
Other proteins in same PDB: d4k4ha1, d4k4ha3, d4k4ha4, d4k4he1, d4k4he3, d4k4he4, d4k4hi1, d4k4hi3, d4k4hi4, d4k4hm1, d4k4hm3, d4k4hm4
automated match to d2bcqa2
protein/DNA complex; complexed with 1rz, act, ca

Domains for 4k4i:

Domain d4k4ia2: 4k4i A:329-385 [266521]
Other proteins in same PDB: d4k4ia1, d4k4ia3, d4k4ia4, d4k4ie1, d4k4ie3, d4k4ie4, d4k4ii1, d4k4ii3, d4k4ii4, d4k4im1, d4k4im3, d4k4im4
automated match to d2bcqa2
protein/DNA complex; complexed with 1ry, act, ca, cac

Domain d4k4ie2: 4k4i E:329-385 [266524]
Other proteins in same PDB: d4k4ia1, d4k4ia3, d4k4ia4, d4k4ie1, d4k4ie3, d4k4ie4, d4k4ii1, d4k4ii3, d4k4ii4, d4k4im1, d4k4im3, d4k4im4
automated match to d2bcqa2
protein/DNA complex; complexed with 1ry, act, ca, cac

Domain d4k4ii2: 4k4i I:329-385 [266527]
Other proteins in same PDB: d4k4ia1, d4k4ia3, d4k4ia4, d4k4ie1, d4k4ie3, d4k4ie4, d4k4ii1, d4k4ii3, d4k4ii4, d4k4im1, d4k4im3, d4k4im4
automated match to d2bcqa2
protein/DNA complex; complexed with 1ry, act, ca, cac

Domain d4k4im2: 4k4i M:329-385 [266530]
Other proteins in same PDB: d4k4ia1, d4k4ia3, d4k4ia4, d4k4ie1, d4k4ie3, d4k4ie4, d4k4ii1, d4k4ii3, d4k4ii4, d4k4im1, d4k4im3, d4k4im4
automated match to d2bcqa2
protein/DNA complex; complexed with 1ry, act, ca, cac

More info for Protein DNA polymerase lambda from a.60.12.1: DNA polymerase beta-like, second domain

Timeline for Protein DNA polymerase lambda from a.60.12.1: DNA polymerase beta-like, second domain:

Protein DNA polymerase lambda from a.60.12.1: DNA polymerase beta-like, second domain first appeared in SCOP 1.67
Protein DNA polymerase lambda from a.60.12.1: DNA polymerase beta-like, second domain appears in SCOPe 2.07