SCOPe 2.06: Protein: Thrombopoietin

Lineage for Protein: Thrombopoietin

Root: SCOPe 2.06
Class a: All alpha proteins [46456] (289 folds)
Fold a.26: 4-helical cytokines [47265] (1 superfamily)
core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
Superfamily a.26.1: 4-helical cytokines [47266] (4 families)
there are two different topoisomers of this fold with different entanglements of the two crossover connections
Family a.26.1.2: Short-chain cytokines [47286] (14 proteins)
Protein Thrombopoietin [101140] (1 species)
long chain cytokine with a short-chain cytokine topology

Species:

Human (Homo sapiens) [TaxId:9606] [101141] (2 PDB entries)

Domains for 1v7m:
1. Domain d1v7mv_: 1v7m V: [100458]
  Other proteins in same PDB: d1v7mh1, d1v7mh2, d1v7mi1, d1v7mi2, d1v7ml1, d1v7ml2, d1v7mm1, d1v7mm2
2. Domain d1v7mx_: 1v7m X: [100459]
  Other proteins in same PDB: d1v7mh1, d1v7mh2, d1v7mi1, d1v7mi2, d1v7ml1, d1v7ml2, d1v7mm1, d1v7mm2

Domains for 1v7n:

Domain d1v7nv_: 1v7n V: [100476]
Other proteins in same PDB: d1v7nh1, d1v7nh2, d1v7ni1, d1v7ni2, d1v7nj1, d1v7nj2, d1v7nk1, d1v7nk2, d1v7nl1, d1v7nl2, d1v7nm1, d1v7nm2, d1v7nn1, d1v7nn2, d1v7no1, d1v7no2

Domain d1v7nx_: 1v7n X: [100477]
Other proteins in same PDB: d1v7nh1, d1v7nh2, d1v7ni1, d1v7ni2, d1v7nj1, d1v7nj2, d1v7nk1, d1v7nk2, d1v7nl1, d1v7nl2, d1v7nm1, d1v7nm2, d1v7nn1, d1v7nn2, d1v7no1, d1v7no2

Domain d1v7ny_: 1v7n Y: [100478]
Other proteins in same PDB: d1v7nh1, d1v7nh2, d1v7ni1, d1v7ni2, d1v7nj1, d1v7nj2, d1v7nk1, d1v7nk2, d1v7nl1, d1v7nl2, d1v7nm1, d1v7nm2, d1v7nn1, d1v7nn2, d1v7no1, d1v7no2

Domain d1v7nz_: 1v7n Z: [100479]
Other proteins in same PDB: d1v7nh1, d1v7nh2, d1v7ni1, d1v7ni2, d1v7nj1, d1v7nj2, d1v7nk1, d1v7nk2, d1v7nl1, d1v7nl2, d1v7nm1, d1v7nm2, d1v7nn1, d1v7nn2, d1v7no1, d1v7no2

More info for Protein Thrombopoietin from a.26.1.2: Short-chain cytokines

Timeline for Protein Thrombopoietin from a.26.1.2: Short-chain cytokines:

Protein Thrombopoietin from a.26.1.2: Short-chain cytokines first appeared in SCOP 1.67
Protein Thrombopoietin from a.26.1.2: Short-chain cytokines appears in SCOPe 2.05
Protein Thrombopoietin from a.26.1.2: Short-chain cytokines appears in SCOPe 2.07
Protein Thrombopoietin from a.26.1.2: Short-chain cytokines appears in the current release, SCOPe 2.08