SCOPe 2.04: Family a.4.5.46: La domain

Lineage for Family a.4.5.46: La domain

1. Root: SCOPe 2.04

2. Class a: All alpha proteins [46456] (285 folds)

3. Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
   core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down

4. Superfamily a.4.5: "Winged helix" DNA-binding domain [46785] (85 families)
   contains a small beta-sheet (wing)

5. Family a.4.5.46: La domain [101051] (2 proteins)
   Pfam PF05383; RNA-binding domain

Proteins:

1. La-related protein 4 LARP4 [140271] (1 species)
   C-mpl binding protein

   • Species Human (Homo sapiens) [TaxId:9606] [140272] (1 PDB entry)
     Uniprot Q71RC2 112-199

2. Lupus La autoantigen N-terminal domain [101052] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [101053] (7 PDB entries)

   2. Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [101054] (1 PDB entry)

More info for Family a.4.5.46: La domain

Timeline for Family a.4.5.46: La domain:

• Family a.4.5.46: La domain first appeared in SCOP 1.67
  
• Family a.4.5.46: La domain appears in SCOPe 2.03
  
• Family a.4.5.46: La domain appears in SCOPe 2.05
  
• Family a.4.5.46: La domain appears in the current release, SCOPe 2.08