SCOP 1.69: Family c.47.1.13: DsbA-like

Lineage for Family c.47.1.13: DsbA-like

1. Root: SCOP 1.69

2. Class c: Alpha and beta proteins (a/b) [51349] (136 folds)

3. Fold c.47: Thioredoxin fold [52832] (2 superfamilies)
   core: 3 layers, a/b/a; mixed beta-sheet of 4 strands, order 4312; strand 3 is antiparallel to the rest

4. Superfamily c.47.1: Thioredoxin-like [52833] (15 families)

5. Family c.47.1.13: DsbA-like [100953] (2 proteins)
   contains an all-alpha subdomain insertion

Proteins:

1. Disulfide-bond formation facilitator (DsbA) [100954] (2 species)
   the insert subdomain is a 4-helical bundle

   1. Species Escherichia coli [TaxId:562] [100955] (12 PDB entries)

   2. Species Vibrio cholerae [TaxId:666] [100956] (1 PDB entry)
      TcpG, periplasmic enzyme required for the maturation of secreted virulence factors

2. Mitochondrial class kappa glutathione S-transferase [102437] (1 species)
   contains larger and less compact insertion in the common fold than DsbA

   • Species Rat (Rattus norvegicus) [TaxId:10116] [102438] (1 PDB entry)

More info for Family c.47.1.13: DsbA-like

Timeline for Family c.47.1.13: DsbA-like:

• Family c.47.1.13: DsbA-like first appeared in SCOP 1.67
  
• Family c.47.1.13: DsbA-like appears in SCOP 1.71
  
• Family c.47.1.13: DsbA-like appears in the current release, SCOPe 2.08