Lineage for Species: Cryptosporidium hominis [TaxId: 237895]

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.117: Thymidylate synthase/dCMP hydroxymethylase [55830] (1 superfamily)
    contains large mixed beta-sheet
  4. Superfamily d.117.1: Thymidylate synthase/dCMP hydroxymethylase [55831] (2 families) (S)
    automatically mapped to Pfam PF00303
  5. Family d.117.1.1: Thymidylate synthase/dCMP hydroxymethylase [55832] (4 proteins)
  6. Protein Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain [55841] (2 species)
  7. Species Cryptosporidium hominis [TaxId:237895] [100887] (16 PDB entries)

PDB entries in Species: Cryptosporidium hominis [TaxId: 237895]:

  1. Domain(s) for 1qzf:
    1. Domain d1qzfa2: 1qzf A:181-521 [96634]
      Other proteins in same PDB: d1qzfa1, d1qzfb1, d1qzfc1, d1qzfd1, d1qzfe1
      complexed with cb3, fol, ndp, ump
    2. Domain d1qzfb2: 1qzf B:181-521 [96636]
      Other proteins in same PDB: d1qzfa1, d1qzfb1, d1qzfc1, d1qzfd1, d1qzfe1
      complexed with cb3, fol, ndp, ump
    3. Domain d1qzfc2: 1qzf C:181-521 [96638]
      Other proteins in same PDB: d1qzfa1, d1qzfb1, d1qzfc1, d1qzfd1, d1qzfe1
      complexed with cb3, fol, ndp, ump
    4. Domain d1qzfd2: 1qzf D:181-521 [96640]
      Other proteins in same PDB: d1qzfa1, d1qzfb1, d1qzfc1, d1qzfd1, d1qzfe1
      complexed with cb3, fol, ndp, ump
    5. Domain d1qzfe2: 1qzf E:181-521 [96642]
      Other proteins in same PDB: d1qzfa1, d1qzfb1, d1qzfc1, d1qzfd1, d1qzfe1
      complexed with cb3, fol, ndp, ump
  2. Domain(s) for 1sej:
    1. Domain d1seja2: 1sej A:181-521 [105456]
      Other proteins in same PDB: d1seja1, d1sejb1, d1sejc1, d1sejd1, d1seje1
      Q5CGA3 Q27552
      complexed with f89, ndp, ump
    2. Domain d1sejb2: 1sej B:181-521 [105458]
      Other proteins in same PDB: d1seja1, d1sejb1, d1sejc1, d1sejd1, d1seje1
      Q5CGA3 Q27552
      complexed with f89, ndp, ump
    3. Domain d1sejc2: 1sej C:181-521 [105460]
      Other proteins in same PDB: d1seja1, d1sejb1, d1sejc1, d1sejd1, d1seje1
      Q5CGA3 Q27552
      complexed with f89, ndp, ump
    4. Domain d1sejd2: 1sej D:181-521 [105462]
      Other proteins in same PDB: d1seja1, d1sejb1, d1sejc1, d1sejd1, d1seje1
      Q5CGA3 Q27552
      complexed with f89, ndp, ump
    5. Domain d1seje2: 1sej E:181-521 [105464]
      Other proteins in same PDB: d1seja1, d1sejb1, d1sejc1, d1sejd1, d1seje1
      Q5CGA3 Q27552
      complexed with f89, ndp, ump
  3. Domain(s) for 4ky8:
    1. Domain d4ky8a2: 4ky8 A:193-521 [253461]
      Other proteins in same PDB: d4ky8a1, d4ky8b1, d4ky8c1, d4ky8d1, d4ky8e1
      automated match to d1qzfa2
      complexed with 1uf, mtx, ndp, ufp
    2. Domain d4ky8b2: 4ky8 B:193-521 [253463]
      Other proteins in same PDB: d4ky8a1, d4ky8b1, d4ky8c1, d4ky8d1, d4ky8e1
      automated match to d1qzfa2
      complexed with 1uf, mtx, ndp, ufp
    3. Domain d4ky8c2: 4ky8 C:193-521 [253465]
      Other proteins in same PDB: d4ky8a1, d4ky8b1, d4ky8c1, d4ky8d1, d4ky8e1
      automated match to d1qzfa2
      complexed with 1uf, mtx, ndp, ufp
    4. Domain d4ky8d2: 4ky8 D:193-521 [253467]
      Other proteins in same PDB: d4ky8a1, d4ky8b1, d4ky8c1, d4ky8d1, d4ky8e1
      automated match to d1qzfa2
      complexed with 1uf, mtx, ndp, ufp
    5. Domain d4ky8e2: 4ky8 E:193-521 [253469]
      Other proteins in same PDB: d4ky8a1, d4ky8b1, d4ky8c1, d4ky8d1, d4ky8e1
      automated match to d1qzfa2
      complexed with 1uf, mtx, ndp, ufp
  4. Domain(s) for 4q0e:
    1. Domain d4q0ea2: 4q0e A:193-521 [260371]
      Other proteins in same PDB: d4q0ea1, d4q0eb1, d4q0ec1, d4q0ed1, d4q0ee1
      automated match to d1seja2
      complexed with 2xb, ndp, ufp
    2. Domain d4q0eb2: 4q0e B:193-521 [260369]
      Other proteins in same PDB: d4q0ea1, d4q0eb1, d4q0ec1, d4q0ed1, d4q0ee1
      automated match to d1seja2
      complexed with 2xb, ndp, ufp
    3. Domain d4q0ec2: 4q0e C:193-521 [260373]
      Other proteins in same PDB: d4q0ea1, d4q0eb1, d4q0ec1, d4q0ed1, d4q0ee1
      automated match to d1seja2
      complexed with 2xb, ndp, ufp
    4. Domain d4q0ed2: 4q0e D:193-521 [260377]
      Other proteins in same PDB: d4q0ea1, d4q0eb1, d4q0ec1, d4q0ed1, d4q0ee1
      automated match to d1seja2
      complexed with 2xb, ndp, ufp
    5. Domain d4q0ee2: 4q0e E:193-521 [260375]
      Other proteins in same PDB: d4q0ea1, d4q0eb1, d4q0ec1, d4q0ed1, d4q0ee1
      automated match to d1seja2
      complexed with 2xb, ndp, ufp
  5. Domain(s) for 6pf7:
    1. Domain d6pf7a2: 6pf7 A:193-521 [375066]
      Other proteins in same PDB: d6pf7a1, d6pf7b1, d6pf7c1, d6pf7d1, d6pf7e1
      automated match to d1qzfa2
      complexed with mtx, ndp, og7, so4, ufp
    2. Domain d6pf7b2: 6pf7 B:193-521 [375112]
      Other proteins in same PDB: d6pf7a1, d6pf7b1, d6pf7c1, d6pf7d1, d6pf7e1
      automated match to d1qzfa2
      complexed with mtx, ndp, og7, so4, ufp
    3. Domain d6pf7c2: 6pf7 C:181-521 [375139]
      Other proteins in same PDB: d6pf7a1, d6pf7b1, d6pf7c1, d6pf7d1, d6pf7e1
      automated match to d1qzfa2
      complexed with mtx, ndp, og7, so4, ufp
    4. Domain d6pf7d2: 6pf7 D:193-521 [375064]
      Other proteins in same PDB: d6pf7a1, d6pf7b1, d6pf7c1, d6pf7d1, d6pf7e1
      automated match to d1qzfa2
      complexed with mtx, ndp, og7, so4, ufp
    5. Domain d6pf7e2: 6pf7 E:181-521 [375130]
      Other proteins in same PDB: d6pf7a1, d6pf7b1, d6pf7c1, d6pf7d1, d6pf7e1
      automated match to d1qzfa2
      complexed with mtx, ndp, og7, so4, ufp
  6. Domain(s) for 6pf8:
    1. Domain d6pf8a2: 6pf8 A:193-521 [375077]
      Other proteins in same PDB: d6pf8a1, d6pf8b1, d6pf8c1, d6pf8d1, d6pf8e1
      automated match to d1qzfa2
      complexed with mtx, ndp, oe7, ufp
    2. Domain d6pf8b2: 6pf8 B:193-521 [375135]
      Other proteins in same PDB: d6pf8a1, d6pf8b1, d6pf8c1, d6pf8d1, d6pf8e1
      automated match to d1qzfa2
      complexed with mtx, ndp, oe7, ufp
    3. Domain d6pf8c2: 6pf8 C:193-521 [375122]
      Other proteins in same PDB: d6pf8a1, d6pf8b1, d6pf8c1, d6pf8d1, d6pf8e1
      automated match to d1qzfa2
      complexed with mtx, ndp, oe7, ufp
    4. Domain d6pf8d2: 6pf8 D:193-521 [375096]
      Other proteins in same PDB: d6pf8a1, d6pf8b1, d6pf8c1, d6pf8d1, d6pf8e1
      automated match to d1qzfa2
      complexed with mtx, ndp, oe7, ufp
    5. Domain d6pf8e2: 6pf8 E:193-521 [375045]
      Other proteins in same PDB: d6pf8a1, d6pf8b1, d6pf8c1, d6pf8d1, d6pf8e1
      automated match to d1qzfa2
      complexed with mtx, ndp, oe7, ufp
  7. Domain(s) for 6pf9:
    1. Domain d6pf9a2: 6pf9 A:193-521 [375068]
      Other proteins in same PDB: d6pf9a1, d6pf9b1, d6pf9c1, d6pf9d1, d6pf9e1
      automated match to d1qzfa2
      complexed with mtx, ndp, of7, so4, ufp
    2. Domain d6pf9b2: 6pf9 B:193-521 [375109]
      Other proteins in same PDB: d6pf9a1, d6pf9b1, d6pf9c1, d6pf9d1, d6pf9e1
      automated match to d1qzfa2
      complexed with mtx, ndp, of7, so4, ufp
    3. Domain d6pf9c2: 6pf9 C:193-521 [375094]
      Other proteins in same PDB: d6pf9a1, d6pf9b1, d6pf9c1, d6pf9d1, d6pf9e1
      automated match to d1qzfa2
      complexed with mtx, ndp, of7, so4, ufp
    4. Domain d6pf9d2: 6pf9 D:193-521 [375073]
      Other proteins in same PDB: d6pf9a1, d6pf9b1, d6pf9c1, d6pf9d1, d6pf9e1
      automated match to d1qzfa2
      complexed with mtx, ndp, of7, so4, ufp
    5. Domain d6pf9e2: 6pf9 E:193-521 [375047]
      Other proteins in same PDB: d6pf9a1, d6pf9b1, d6pf9c1, d6pf9d1, d6pf9e1
      automated match to d1qzfa2
      complexed with mtx, ndp, of7, so4, ufp
  8. Domain(s) for 6pfa:
    1. Domain d6pfaa2: 6pfa A:193-521 [375154]
      Other proteins in same PDB: d6pfaa1, d6pfab1, d6pfac1, d6pfad1, d6pfae1
      automated match to d1qzfa2
      complexed with mtx, ndp, of4, so4, ufp
    2. Domain d6pfab2: 6pfa B:193-521 [375033]
      Other proteins in same PDB: d6pfaa1, d6pfab1, d6pfac1, d6pfad1, d6pfae1
      automated match to d1qzfa2
      complexed with mtx, ndp, of4, so4, ufp
    3. Domain d6pfac2: 6pfa C:193-521 [375062]
      Other proteins in same PDB: d6pfaa1, d6pfab1, d6pfac1, d6pfad1, d6pfae1
      automated match to d1qzfa2
      complexed with mtx, ndp, of4, so4, ufp
    4. Domain d6pfad2: 6pfa D:193-521 [375141]
      Other proteins in same PDB: d6pfaa1, d6pfab1, d6pfac1, d6pfad1, d6pfae1
      automated match to d1qzfa2
      complexed with mtx, ndp, of4, so4, ufp
    5. Domain d6pfae2: 6pfa E:193-521 [375054]
      Other proteins in same PDB: d6pfaa1, d6pfab1, d6pfac1, d6pfad1, d6pfae1
      automated match to d1qzfa2
      complexed with mtx, ndp, of4, so4, ufp
  9. Domain(s) for 6pfb:
    1. Domain d6pfba2: 6pfb A:193-521 [375049]
      Other proteins in same PDB: d6pfba1, d6pfbb1, d6pfbc1, d6pfbd1, d6pfbe1
      automated match to d1qzfa2
      complexed with mtx, ndp, og4, ufp
    2. Domain d6pfbb2: 6pfb B:193-521 [375158]
      Other proteins in same PDB: d6pfba1, d6pfbb1, d6pfbc1, d6pfbd1, d6pfbe1
      automated match to d1qzfa2
      complexed with mtx, ndp, og4, ufp
    3. Domain d6pfbc2: 6pfb C:193-521 [375058]
      Other proteins in same PDB: d6pfba1, d6pfbb1, d6pfbc1, d6pfbd1, d6pfbe1
      automated match to d1qzfa2
      complexed with mtx, ndp, og4, ufp
    4. Domain d6pfbd2: 6pfb D:193-521 [375075]
      Other proteins in same PDB: d6pfba1, d6pfbb1, d6pfbc1, d6pfbd1, d6pfbe1
      automated match to d1qzfa2
      complexed with mtx, ndp, og4, ufp
    5. Domain d6pfbe2: 6pfb E:193-521 [375039]
      Other proteins in same PDB: d6pfba1, d6pfbb1, d6pfbc1, d6pfbd1, d6pfbe1
      automated match to d1qzfa2
      complexed with mtx, ndp, og4, ufp
  10. Domain(s) for 6pfc:
    1. Domain d6pfca2: 6pfc A:193-521 [375816]
      Other proteins in same PDB: d6pfca1, d6pfcb1, d6pfcc1, d6pfcd1, d6pfce1
      automated match to d1qzfa2
      complexed with mtx, ndp, oed, ufp
    2. Domain d6pfcb2: 6pfc B:193-521 [375820]
      Other proteins in same PDB: d6pfca1, d6pfcb1, d6pfcc1, d6pfcd1, d6pfce1
      automated match to d1qzfa2
      complexed with mtx, ndp, oed, ufp
    3. Domain d6pfcc2: 6pfc C:193-521 [375828]
      Other proteins in same PDB: d6pfca1, d6pfcb1, d6pfcc1, d6pfcd1, d6pfce1
      automated match to d1qzfa2
      complexed with mtx, ndp, oed, ufp
    4. Domain d6pfcd2: 6pfc D:193-521 [375844]
      Other proteins in same PDB: d6pfca1, d6pfcb1, d6pfcc1, d6pfcd1, d6pfce1
      automated match to d1qzfa2
      complexed with mtx, ndp, oed, ufp
    5. Domain d6pfce2: 6pfc E:193-521 [375822]
      Other proteins in same PDB: d6pfca1, d6pfcb1, d6pfcc1, d6pfcd1, d6pfce1
      automated match to d1qzfa2
      complexed with mtx, ndp, oed, ufp
  11. Domain(s) for 6pfe:
    1. Domain d6pfea2: 6pfe A:193-521 [375035]
      Other proteins in same PDB: d6pfea1, d6pfeb1, d6pfec1, d6pfed1, d6pfee1
      automated match to d1qzfa2
      complexed with mtx, ndp, oea, ufp
    2. Domain d6pfeb2: 6pfe B:193-521 [375235]
      Other proteins in same PDB: d6pfea1, d6pfeb1, d6pfec1, d6pfed1, d6pfee1
      automated match to d1qzfa2
      complexed with mtx, ndp, oea, ufp
    3. Domain d6pfec2: 6pfe C:181-521 [375041]
      Other proteins in same PDB: d6pfea1, d6pfeb1, d6pfec1, d6pfed1, d6pfee1
      automated match to d1qzfa2
      complexed with mtx, ndp, oea, ufp
    4. Domain d6pfed2: 6pfe D:181-521 [375083]
      Other proteins in same PDB: d6pfea1, d6pfeb1, d6pfec1, d6pfed1, d6pfee1
      automated match to d1qzfa2
      complexed with mtx, ndp, oea, ufp
    5. Domain d6pfee2: 6pfe E:193-521 [375179]
      Other proteins in same PDB: d6pfea1, d6pfeb1, d6pfec1, d6pfed1, d6pfee1
      automated match to d1qzfa2
      complexed with mtx, ndp, oea, ufp
  12. Domain(s) for 6pff:
    1. Domain d6pffa2: 6pff A:193-521 [375092]
      Other proteins in same PDB: d6pffa1, d6pffb1, d6pffc1, d6pffd1, d6pffe1
      automated match to d1qzfa2
      complexed with mtx, ndp, og1, so4, ufp
    2. Domain d6pffb2: 6pff B:193-521 [375128]
      Other proteins in same PDB: d6pffa1, d6pffb1, d6pffc1, d6pffd1, d6pffe1
      automated match to d1qzfa2
      complexed with mtx, ndp, og1, so4, ufp
    3. Domain d6pffc2: 6pff C:193-521 [375148]
      Other proteins in same PDB: d6pffa1, d6pffb1, d6pffc1, d6pffd1, d6pffe1
      automated match to d1qzfa2
      complexed with mtx, ndp, og1, so4, ufp
    4. Domain d6pffd2: 6pff D:193-521 [375150]
      Other proteins in same PDB: d6pffa1, d6pffb1, d6pffc1, d6pffd1, d6pffe1
      automated match to d1qzfa2
      complexed with mtx, ndp, og1, so4, ufp
    5. Domain d6pffe2: 6pff E:193-521 [375185]
      Other proteins in same PDB: d6pffa1, d6pffb1, d6pffc1, d6pffd1, d6pffe1
      automated match to d1qzfa2
      complexed with mtx, ndp, og1, so4, ufp
  13. Domain(s) for 6pfg:
    1. Domain d6pfga2: 6pfg A:193-521 [375029]
      Other proteins in same PDB: d6pfga1, d6pfgb1, d6pfgc1, d6pfgd1, d6pfge1
      automated match to d1qzfa2
      complexed with mtx, ndp, ofj, so4, ufp
    2. Domain d6pfgb2: 6pfg B:193-521 [375070]
      Other proteins in same PDB: d6pfga1, d6pfgb1, d6pfgc1, d6pfgd1, d6pfge1
      automated match to d1qzfa2
      complexed with mtx, ndp, ofj, so4, ufp
    3. Domain d6pfgc2: 6pfg C:193-521 [375031]
      Other proteins in same PDB: d6pfga1, d6pfgb1, d6pfgc1, d6pfgd1, d6pfge1
      automated match to d1qzfa2
      complexed with mtx, ndp, ofj, so4, ufp
    4. Domain d6pfgd2: 6pfg D:193-521 [375100]
      Other proteins in same PDB: d6pfga1, d6pfgb1, d6pfgc1, d6pfgd1, d6pfge1
      automated match to d1qzfa2
      complexed with mtx, ndp, ofj, so4, ufp
    5. Domain d6pfge2: 6pfg E:193-521 [375102]
      Other proteins in same PDB: d6pfga1, d6pfgb1, d6pfgc1, d6pfgd1, d6pfge1
      automated match to d1qzfa2
      complexed with mtx, ndp, ofj, so4, ufp
  14. Domain(s) for 6pfh:
    1. Domain d6pfha2: 6pfh A:181-521 [375051]
      Other proteins in same PDB: d6pfha1, d6pfhb1, d6pfhc1, d6pfhd1, d6pfhe1
      automated match to d1qzfa2
      complexed with mtx, ndp, ofd, ufp
    2. Domain d6pfhb2: 6pfh B:193-521 [375146]
      Other proteins in same PDB: d6pfha1, d6pfhb1, d6pfhc1, d6pfhd1, d6pfhe1
      automated match to d1qzfa2
      complexed with mtx, ndp, ofd, ufp
    3. Domain d6pfhc2: 6pfh C:193-521 [375087]
      Other proteins in same PDB: d6pfha1, d6pfhb1, d6pfhc1, d6pfhd1, d6pfhe1
      automated match to d1qzfa2
      complexed with mtx, ndp, ofd, ufp
    4. Domain d6pfhd2: 6pfh D:181-521 [375037]
      Other proteins in same PDB: d6pfha1, d6pfhb1, d6pfhc1, d6pfhd1, d6pfhe1
      automated match to d1qzfa2
      complexed with mtx, ndp, ofd, ufp
    5. Domain d6pfhe2: 6pfh E:193-521 [375166]
      Other proteins in same PDB: d6pfha1, d6pfhb1, d6pfhc1, d6pfhd1, d6pfhe1
      automated match to d1qzfa2
      complexed with mtx, ndp, ofd, ufp
  15. Domain(s) for 6pfi:
    1. Domain d6pfia2: 6pfi A:193-521 [375107]
      Other proteins in same PDB: d6pfia1, d6pfib1, d6pfic1, d6pfid1, d6pfie1
      automated match to d1qzfa2
      complexed with mtx, ndp, oep, ufp
    2. Domain d6pfib2: 6pfi B:193-521 [375085]
      Other proteins in same PDB: d6pfia1, d6pfib1, d6pfic1, d6pfid1, d6pfie1
      automated match to d1qzfa2
      complexed with mtx, ndp, oep, ufp
    3. Domain d6pfic2: 6pfi C:193-521 [375060]
      Other proteins in same PDB: d6pfia1, d6pfib1, d6pfic1, d6pfid1, d6pfie1
      automated match to d1qzfa2
      complexed with mtx, ndp, oep, ufp
    4. Domain d6pfid2: 6pfi D:193-521 [375191]
      Other proteins in same PDB: d6pfia1, d6pfib1, d6pfic1, d6pfid1, d6pfie1
      automated match to d1qzfa2
      complexed with mtx, ndp, oep, ufp
    5. Domain d6pfie2: 6pfi E:193-521 [375056]
      Other proteins in same PDB: d6pfia1, d6pfib1, d6pfic1, d6pfid1, d6pfie1
      automated match to d1qzfa2
      complexed with mtx, ndp, oep, ufp
  16. Domain(s) for 6wep:
    1. Domain d6wepa2: 6wep A:193-519 [388020]
      Other proteins in same PDB: d6wepa1, d6wepb1
      automated match to d1qzfa2
      complexed with mtx, ndp
    2. Domain d6wepb2: 6wep B:193-519 [388016]
      Other proteins in same PDB: d6wepa1, d6wepb1
      automated match to d1qzfa2
      complexed with mtx, ndp

More info for Species Cryptosporidium hominis [TaxId:237895] from d.117.1.1 Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain

Timeline for Species Cryptosporidium hominis [TaxId:237895] from d.117.1.1 Bifunctional enzyme dihydrofolate reductase-thymidylate synthase, TS domain: