Lineage for d1v7ny_ (1v7n Y:)

  1. Root: SCOP 1.71
  2. 530466Class a: All alpha proteins [46456] (226 folds)
  3. 536620Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 536621Superfamily a.26.1: 4-helical cytokines [47266] (3 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 536689Family a.26.1.2: Short-chain cytokines [47286] (11 proteins)
  6. 536769Protein Thrombopoietin [101140] (1 species)
    long chain cytokine with a short-chain cytokine topology
  7. 536770Species Human (Homo sapiens) [TaxId:9606] [101141] (2 PDB entries)
  8. 536775Domain d1v7ny_: 1v7n Y: [100478]
    Other proteins in same PDB: d1v7nh1, d1v7nh2, d1v7ni1, d1v7ni2, d1v7nj1, d1v7nj2, d1v7nk1, d1v7nk2, d1v7nl1, d1v7nl2, d1v7nm1, d1v7nm2, d1v7nn1, d1v7nn2, d1v7no1, d1v7no2

Details for d1v7ny_

PDB Entry: 1v7n (more details), 3.3 Å

PDB Description: human thrombopoietin functional domain complexed to neutralizing antibody tn1 fab

SCOP Domain Sequences for d1v7ny_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1v7ny_ a.26.1.2 (Y:) Thrombopoietin {Human (Homo sapiens)}
dlrvlskllrdshvlhsrlsqcpevhplptpvllpavdfslgewktqmeetkaqdilgav
tlllegvmaargqlgptclssllgqlsgqvrlllgalqsllgtqlpprgrttahkdpnai
flsfqhllrgkvrflmlvg

SCOP Domain Coordinates for d1v7ny_:

Click to download the PDB-style file with coordinates for d1v7ny_.
(The format of our PDB-style files is described here.)

Timeline for d1v7ny_: