Lineage for d1v7ni1 (1v7n I:1-116)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2017116Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 2017117Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 protein domains)
  6. 2017323Protein Immunoglobulin heavy chain variable domain, VH [88543] (21 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 2017580Species Mouse (Mus musculus), cluster 1 [TaxId:10090] [88548] (68 PDB entries)
    Uniprot P01796 # ! HV27_MOUSE Ig heavy chain V-III region A4
  8. 2017665Domain d1v7ni1: 1v7n I:1-116 [100462]
    Other proteins in same PDB: d1v7nh2, d1v7ni2, d1v7nj2, d1v7nk2, d1v7nl1, d1v7nl2, d1v7nm1, d1v7nm2, d1v7nn1, d1v7nn2, d1v7no1, d1v7no2, d1v7nv_, d1v7nx_, d1v7ny_, d1v7nz_
    part of anti-trombopoetin Fab tn1

Details for d1v7ni1

PDB Entry: 1v7n (more details), 3.3 Å

PDB Description: Human Thrombopoietin Functional Domain Complexed To Neutralizing Antibody TN1 Fab
PDB Compounds: (I:) Monoclonal TN1 Fab Heavy Chain

SCOPe Domain Sequences for d1v7ni1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1v7ni1 b.1.1.1 (I:1-116) Immunoglobulin heavy chain variable domain, VH {Mouse (Mus musculus), cluster 1 [TaxId: 10090]}
evkleesggglvqpggsmklscaasgftfsdawmdwvrqspekglewvaeirskvnnhai
hyaesvkgrftvsrddskssvylqmnslraedtgiyycsgwsflywgqgtlvtvsa

SCOPe Domain Coordinates for d1v7ni1:

Click to download the PDB-style file with coordinates for d1v7ni1.
(The format of our PDB-style files is described here.)

Timeline for d1v7ni1: