SCOPe 2.05: Domain d1v2xa_: 1v2x A:

Lineage for d1v2xa_ (1v2x A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.116: alpha/beta knot [75216] (1 superfamily)
   core: 3 layers: a/b/a, parallel beta-sheet of 5 strands, order 21435; contains a deep trefoil knot

4. Superfamily c.116.1: alpha/beta knot [75217] (9 families)
   known or predicted SAM-dependent methytransferases including the SPOUT 'sequence' superfamily
   all known members have dimeric structures

5. Family c.116.1.1: SpoU-like RNA 2'-O ribose methyltransferase [75218] (5 proteins)
   contains extra strand (3) in the parallel beta-sheet, order 321546

6. Protein tRNA (Gm18) methyltransferase TrmH [102279] (1 species)

7. Species Thermus thermophilus [TaxId:274] [102280] (1 PDB entry)

8. Domain d1v2xa_: 1v2x A: [100274]
   complexed with po4, sam

Details for d1v2xa_

PDB Entry: 1v2x, 1.5 Å

PDB Description: trmh

PDB Compounds: (A:) tRNA (Gm18) methyltransferase

SCOPe Domain Sequences for d1v2xa_:

Sequence; same for both SEQRES and ATOM records:

>d1v2xa_ c.116.1.1 (A:) tRNA (Gm18) methyltransferase TrmH {Thermus thermophilus [TaxId: 274]}
mrertearrrrieevlrrrqpdltvllenvhkphnlsailrtcdavgvleahavnptggv
ptfnetsggshkwvylrvhpdlheafrflkergftvyatalredardfrevdytkptavl
fgaekwgvseealaladgaikipmlgmvqslnvsvaaavilfeaqrqrlkaglydrprld
pelyqkvladw

Timeline for d1v2xa_:

• d1v2xa_ first appeared in SCOP 1.67
  
• d1v2xa_ appears in SCOPe 2.04
  
• d1v2xa_ appears in SCOPe 2.06
  
• d1v2xa_ appears in the current release, SCOPe 2.08