SCOP 1.71: Domain d1uwva2: 1uwv A:75-432

Lineage for d1uwva2 (1uwv A:75-432)

1. Root: SCOP 1.71

2. Class c: Alpha and beta proteins (a/b) [51349] (134 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (41 families)

5. Family c.66.1.40: (Uracil-5-)-methyltransferase [102581] (1 protein)
   Pfam 05958

6. Protein rRNA (Uracil-5-)-methyltransferase RumA, catalytic domain [102582] (1 species)
   includes an iron-sulfur cluster-binding, alpha+beta sudbomain

7. Species Escherichia coli [TaxId:562] [102583] (1 PDB entry)

8. Domain d1uwva2: 1uwv A:75-432 [100129]
   Other proteins in same PDB: d1uwva1
   complexed with cl, fs4, ni, po4

Details for d1uwva2

PDB Entry: 1uwv, 1.95 Å

PDB Description: crystal structure of ruma, the iron-sulfur cluster containing e. coli 23s ribosomal rna 5-methyluridine methyltransferase

SCOP Domain Sequences for d1uwva2:

Sequence; same for both SEQRES and ATOM records:

>d1uwva2 c.66.1.40 (A:75-432) rRNA (Uracil-5-)-methyltransferase RumA, catalytic domain {Escherichia coli}
eretprcphfgvcggcqqqhasvdlqqrsksaalarlmkhdvseviadvpwgyrrrarls
lnylpktqqlqmgfrkagssdivdvkqcpilapqleallpkvraclgslqamrhlghvel
vqatsgtlmilrhtaplssadreklerfshsegldlylapdseiletvsgempwydsngl
rltfsprdfiqvnagvnqkmvaralewldvqpedrvldlfcgmgnftlplatqaasvvgv
egvpalvekgqqnarlnglqnvtfyhenleedvtkqpwakngfdkvlldparagaagvmq
qiiklepirivyvscnpatlardseallkagytiarlamldmfphtghlesmvlfsrv

Timeline for d1uwva2:

• d1uwva2 first appeared in SCOP 1.67
  
• d1uwva2 appears in SCOP 1.69
  
• d1uwva2 appears in SCOP 1.73
  
• d1uwva2 appears in the current release, SCOPe 2.08