Lineage for d1uwgl1 (1uwg L:1-107)

  1. Root: SCOP 1.75
  2. 781541Class b: All beta proteins [48724] (174 folds)
  3. 781542Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 781543Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 781544Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (32 proteins)
  6. 782637Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (16 species)
    VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 783226Species Mouse (Mus musculus), cluster 4 [TaxId:10090] [88531] (182 PDB entries)
    Uniprot P01645 1-106 # 95% sequense identity; KV5L_MOUSE Ig kappa chain V-V region HP 93G7
    SQ NA # natural chimera; best hits are: Uniprot P01637 (Ig kappa chain V-V region T1) and Uniprot P01837 (Ig kappa chain C region)
    SQ NA # humanized antibody
    SQ NA # part of Fab 28 against HIV-1 RT
    Uniprot P01642 21-115 #
    KV5I_MOUSE Ig kappa chain V-V region L7 precursor
    Uniprot P01645 1-106 # 95% sequense identity; KV5L_MOUSE Ig kappa chain V-V region HP 93G7 ! SQ NA # natural chimera; best hits are: Uniprot P01637 (Ig kappa chain V-V region T1) and Uniprot P01837 (Ig kappa chain C region) ! SQ NA # humanized antibody ! SQ NA # part of Fab 28 against HIV-1 RT ! Uniprot P01642 21-115 # ! KV5I_MOUSE Ig kappa chain V-V region L7 precursor
  8. 783402Domain d1uwgl1: 1uwg L:1-107 [100117]
    Other proteins in same PDB: d1uwgh1, d1uwgh2, d1uwgl2, d1uwgx2, d1uwgy1, d1uwgy2
    part of catalytic Fab 14d9

Details for d1uwgl1

PDB Entry: 1uwg (more details), 2.79 Å

PDB Description: molecular mechanism of enantioselective proton transfer to carbon in catalytic antibody 14d9
PDB Compounds: (L:) antibody 14d9

SCOP Domain Sequences for d1uwgl1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1uwgl1 b.1.1.1 (L:1-107) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 4 [TaxId: 10090]}
elvmtqspkfmstsvgdrvsvtckasqnvgthvawyqqkpgqspktliysasyrysgvpd
rftgsgsgtdftltirdvqsedaaeyfcqqynlfpvtfgggtkleik

SCOP Domain Coordinates for d1uwgl1:

Click to download the PDB-style file with coordinates for d1uwgl1.
(The format of our PDB-style files is described here.)

Timeline for d1uwgl1: