SCOP 1.71: Domain d1uwel1: 1uwe L:1-107

Lineage for d1uwel1 (1uwe L:1-107)

1. Root: SCOP 1.71

2. Class b: All beta proteins [48724] (149 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (25 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (28 proteins)

6. Protein Immunoglobulin light chain kappa variable domain, VL-kappa [88519] (14 species)
   VL-kappa domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VL-kappa domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Mouse (Mus musculus), cluster 4 [TaxId:10090] [88531] (170 PDB entries)

8. Domain d1uwel1: 1uwe L:1-107 [100105]
   Other proteins in same PDB: d1uweh1, d1uweh2, d1uwel2, d1uweu2, d1uwev1, d1uwev2, d1uwex2, d1uwey1, d1uwey2

Details for d1uwel1

PDB Entry: 1uwe, 2.67 Å

PDB Description: molecular mechanism of enantioselective proton transfer to carbon in catalytic antibody 14d9

SCOP Domain Sequences for d1uwel1:

Sequence; same for both SEQRES and ATOM records:

>d1uwel1 b.1.1.1 (L:1-107) Immunoglobulin light chain kappa variable domain, VL-kappa {Mouse (Mus musculus), cluster 4}
ldnvmtqspsfmstsvgdrvsvtcaasqnvgtnvawyqqkpgqppkaliystsyrysgvp
drftgsgsgtdftltisnvnsedlaeyfcqqyniypvtfgggtkleik

Timeline for d1uwel1:

• d1uwel1 first appeared in SCOP 1.67
  
• d1uwel1 appears in SCOP 1.69
  
• d1uwel1 appears in SCOP 1.73
  
• d1uwel1 appears in the current release, SCOPe 2.08