SCOP 1.69: Domain d1uvra_: 1uvr A:

Lineage for d1uvra_ (1uvr A:)

1. Root: SCOP 1.69

2. Class d: Alpha and beta proteins (a+b) [53931] (279 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (53 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein 3-phosphoinositide dependent protein kinase-1 Pdk1 [90036] (1 species)
   AGC group; PBK subfamily; serine/threonine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [90037] (8 PDB entries)

8. Domain d1uvra_: 1uvr A: [100066]

Details for d1uvra_

PDB Entry: 1uvr, 2.81 Å

PDB Description: structure of human pdk1 kinase domain in complex with bim-8

SCOP Domain Sequences for d1uvra_:

Sequence, based on SEQRES records:

>d1uvra_ d.144.1.7 (A:) 3-phosphoinositide dependent protein kinase-1 Pdk1 {Human (Homo sapiens)}
ppqprkkrpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtre
rdvmsrldhpffvklyftfqddeklyfglsyakngellkyirkigsfdetctrfytaeiv
saleylhgkgiihrdlkpenillnedmhiqitdfgtakvlspeskqaransfvgtaqyvs
pellteksackssdlwalgciiyqlvaglppfragneylifqkiikleydfpekffpkar
dlvekllvldatkrlgceemegygplkahpffesvtwenlhqqtppklt

Sequence, based on observed residues (ATOM records):

>d1uvra_ d.144.1.7 (A:) 3-phosphoinositide dependent protein kinase-1 Pdk1 {Human (Homo sapiens)}
ppqprkkrpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtre
rdvmsrldhpffvklyftfqddeklyfglsyakngellkyirkigsfdetctrfytaeiv
saleylhgkgiihrdlkpenillnedmhiqitdfgtakvlsparansfvgtaqyvspell
teksackssdlwalgciiyqlvaglppfragneylifqkiikleydfpekffpkardlve
kllvldatkrlgceemegygplkahpffesvtwenlhqqtppklt

Timeline for d1uvra_:

• d1uvra_ first appeared in SCOP 1.67
  
• d1uvra_ appears in SCOP 1.71
  
• d1uvra_ appears in the current release, SCOPe 2.08