SCOPe 2.06: Domain d1uvqb1: 1uvq B:95-191

Lineage for d1uvqb1 (1uvq B:95-191)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Class II MHC beta chain, C-terminal domain [88625] (6 species)

7. Species Human (Homo sapiens), HLA-DQ group [TaxId:9606] [88630] (3 PDB entries)
   probably orthologous to the mouse I-A group

8. Domain d1uvqb1: 1uvq B:95-191 [100064]
   Other proteins in same PDB: d1uvqa1, d1uvqa2, d1uvqb2
   complexed with a hypocretin peptide
   complexed with acy, gly, nag, zn

Details for d1uvqb1

PDB Entry: 1uvq, 1.8 Å

PDB Description: crystal structure of hla-dq0602 in complex with a hypocretin peptide

PDB Compounds: (B:) hla class II histocompatibility antigen

SCOPe Domain Sequences for d1uvqb1:

Sequence, based on SEQRES records:

>d1uvqb1 b.1.1.2 (B:95-191) Class II MHC beta chain, C-terminal domain {Human (Homo sapiens), HLA-DQ group [TaxId: 9606]}
veptvtispsrtealnhhnllvcsvtdfypgqikvrwfrndqeetagvvstplirngdwt
fqilvmlemtpqrgdvytchvehpslqspitvewraq

Sequence, based on observed residues (ATOM records):

>d1uvqb1 b.1.1.2 (B:95-191) Class II MHC beta chain, C-terminal domain {Human (Homo sapiens), HLA-DQ group [TaxId: 9606]}
veptvtispsnllvcsvtdfypgqikvrwfrndqeetagvvstplirngdwtfqilvmle
mtpqrgdvytchvehpslqspitvewraq

Timeline for d1uvqb1:

• d1uvqb1 first appeared in SCOP 1.67
  
• d1uvqb1 appears in SCOPe 2.05
  
• d1uvqb1 appears in SCOPe 2.07
  
• d1uvqb1 appears in the current release, SCOPe 2.08