Lineage for d5f2sb_ (5f2s B:)

  1. Root: SCOPe 2.08
  2. Class b: All beta proteins [48724] (180 folds)
  3. Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
    one turn of helix is made by two pairs of antiparallel strands linked with short turns
    has appearance of a sandwich of distinct architecture and jelly-roll topology
  4. Superfamily b.82.2: Clavaminate synthase-like [51197] (16 families) (S)
    Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold
  5. Family b.82.2.14: Jumonji domain / Histone demethylase core [254153] (7 proteins)
    Jumonji domain; Pfam PF02375 (JmjN) and Pfam PF02373 (JmjC); relationship to FIH1 (b.82.2.6) described in PubMed 16983801
    Pfam PF02375 (JmjN) and Pfam PF02373 (JmjC); relationship to FIH1 (b.82.2.6) described in PubMed 16983801; some members include C-terminal helical subdomain (Pfam PF17811)
  6. Protein JMJD2A core [254342] (1 species)
  7. Species Human (Homo sapiens) [TaxId:9606] [254775] (57 PDB entries)
  8. Domain d5f2sb_: 5f2s B: [313864]
    automated match to d4v2wb_
    complexed with 5tz, cl, dms, edo, zn

Details for d5f2sb_

PDB Entry: 5f2s (more details), 2.08 Å

PDB Description: crystal structure of human kdm4a in complex with compound 15
PDB Compounds: (B:) lysine-specific demethylase 4a

SCOPe Domain Sequences for d5f2sb_:

Sequence, based on SEQRES records: (download)

>d5f2sb_ b.82.2.14 (B:) JMJD2A core {Human (Homo sapiens) [TaxId: 9606]}
masesetlnpsarimtfyptmeefrnfsryiayiesqgahraglakvvppkewkprasyd
diddlvipapiqqlvtgqsglftqyniqkkamtvrefrkiansdkyctprysefeelerk
ywknltfnppiygadvngtlyekhvdewnigrlrtildlvekesgitiegvntpylyfgm
wktsfawhtedmdlysinylhfgepkswysvppehgkrlerlakgffpgsaqsceaflrh
kmtlisplmlkkygipfdkvtqeagefmitfpygyhagfnhgfncaestnfatrrwieyg
kqavlcscrkdmvkismdvfvrkfqperyklwkagkdntvidhtlptpeaaefl

Sequence, based on observed residues (ATOM records): (download)

>d5f2sb_ b.82.2.14 (B:) JMJD2A core {Human (Homo sapiens) [TaxId: 9606]}
masesetlnpsarimtfyptmeefrnfsryiayiesqgahraglakvvppkewkprasyd
diddlvipapiqqlvtgqsglftqyniqkkamtvrefrkiansdkyctprysefeelerk
ywknltfnppiygadvngtlyekhvdewnigrlrtildlvekesgitiegvntpylyfgm
wktsfawhtedmdlysinylhfgepkswysvppehgkrlerlakgffpgsaqsceaflrh
kmtlisplmlkkygipfdkvtqeagefmitfpygyhagfnhgfncaestnfatrrwieyg
kqavlcscrmvkismdvfvrkfqperyklwkagkdntvidhtlptpeaaefl

SCOPe Domain Coordinates for d5f2sb_ are not available.

Timeline for d5f2sb_:

View in 3D
Domains from other chains:
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d5f2sa_, d5f2sc_, d5f2sd_