Lineage for d5a1fa1 (5a1f A:26-622)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2814470Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
    one turn of helix is made by two pairs of antiparallel strands linked with short turns
    has appearance of a sandwich of distinct architecture and jelly-roll topology
  4. 2815433Superfamily b.82.2: Clavaminate synthase-like [51197] (16 families) (S)
    Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold
  5. 2815818Family b.82.2.14: Jumonji domain / Histone demethylase core [254153] (7 proteins)
    Jumonji domain; Pfam PF02375 (JmjN) and Pfam PF02373 (JmjC); relationship to FIH1 (b.82.2.6) described in PubMed 16983801
    Pfam PF02375 (JmjN) and Pfam PF02373 (JmjC); relationship to FIH1 (b.82.2.6) described in PubMed 16983801; some members include C-terminal helical subdomain (Pfam PF17811)
  6. 2816275Protein KDM5B (JARID1B or PLU1) core [419085] (1 species)
  7. 2816276Species Human (Homo sapiens) [TaxId:9606] [419582] (14 PDB entries)
  8. 2816282Domain d5a1fa1: 5a1f A:26-622 [414552]
    Other proteins in same PDB: d5a1fa2, d5a1fa3
    complexed with edo, epe, mn, oga, po4, zn

Details for d5a1fa1

PDB Entry: 5a1f (more details), 2.1 Å

PDB Description: crystal structure of the catalytic domain of plu1 in complex with n-oxalylglycine.
PDB Compounds: (A:) lysine-specific demethylase 5b, lysine-specific demethylase 5b

SCOPe Domain Sequences for d5a1fa1:

Sequence, based on SEQRES records: (download)

>d5a1fa1 b.82.2.14 (A:26-622) KDM5B (JARID1B or PLU1) core {Human (Homo sapiens) [TaxId: 9606]}
flpppecpvfepsweefadpfafihkirpiaeqtgickvrpppdwqppfacdvdklhftp
riqrlneleaqtrvklardytlrtfgemadafksdyfnmpvhmvptelvekefwrlvsti
eedvtveygadiaskefgsgfpvrdgkiklspeeeeyldsgwnlnnmpvmeqsvlahita
dicgmklpwlyvgmcfssfcwhiedhwsysinylhwgepktwygvpgyaaeqlenvmkkl
apelfvsqpdllhqlvtimnpntlmthevpvyrtnqcagefvitfprayhsgfnqgfnfa
eavnfctvdwlplgrqcvehyrllh

Sequence, based on observed residues (ATOM records): (download)

>d5a1fa1 b.82.2.14 (A:26-622) KDM5B (JARID1B or PLU1) core {Human (Homo sapiens) [TaxId: 9606]}
flpppecpvfepsweefadpfafihkirpiaeqtgickvrpppdwqppfacdvdklhftp
riqrlneleaqtrvrdytlrtfgemadafksdyfnmpvhmvptelvekefwrlvstieed
vtveygadiaskefgsgfpvrdspeeeeyldsgwnlnnmpvmeqsvlahitadicgmklp
wlyvgmcfssfcwhiedhwsysinylhwgepktwygvpgyaaeqlenvmkklapelfvsq
pdllhqlvtimnpntlmthevpvyrtnqcagefvitfprayhsgfnqgfnfaeavnfctv
dwlplgrqcvehyrllh

SCOPe Domain Coordinates for d5a1fa1:

Click to download the PDB-style file with coordinates for d5a1fa1.
(The format of our PDB-style files is described here.)

Timeline for d5a1fa1:

  • d5a1fa1 is new in SCOPe 2.08-stable