Lineage for d4v04b_ (4v04 B:)
- Root: SCOPe 2.05
Class d: Alpha and beta proteins (a+b) [53931] (381 folds) 
Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
consists of two alpha+beta domains, C-terminal domain is mostly alpha helicalSuperfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) 
shares functional and structural similarities with the ATP-grasp fold and PIPK
Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
members organized in the groups and subfamiles specified by the comments
Protein Fibroblast growth factor receptor 1 [56158] (1 species)
PTK group; FGFR subfamily; membrane spanning protein tyrosine kinaseSpecies Human (Homo sapiens) [TaxId:9606] [56159] (29 PDB entries) 
Domain d4v04b_: 4v04 B: [262048]
automated match to d4nkab_
complexed with 0li, edo, so4
Details for d4v04b_
PDB Entry: 4v04 (more details), 2.12 Å
PDB Description: fgfr1 in complex with ponatinib.
PDB Compounds: (B:) fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, pfeiffer syndrome), isoform cra_bSCOPe Domain Sequences for d4v04b_:
Sequence, based on SEQRES records: (download)
>d4v04b_ d.144.1.7 (B:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
agvseyelpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlk
sdatekdlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarr
ppgleysynpshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvm
kiadfglardihhidyykkttngrlpvkwmapealfdriythqsdvwsfgvllweiftlg
gspypgvpveelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldri
valtsnqe
Sequence, based on observed residues (ATOM records): (download)
>d4v04b_ d.144.1.7 (B:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
agvseyelpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlk
sdatekdlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarr
ppeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfglidyykk
ttngrlpvkwmapealfdriythqsdvwsfgvllweiftlggspypgvpveelfkllkeg
hrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldrivaltsnqe
SCOPe Domain Coordinates for d4v04b_:
Click to download the PDB-style file with coordinates for d4v04b_.
(The format of our PDB-style files is described here.)
(The format of our PDB-style files is described here.)
Timeline for d4v04b_:
- d4v04b_ first appeared in SCOPe 2.04
- d4v04b_ appears in SCOPe 2.06
- d4v04b_ appears in the current release, SCOPe 2.08
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