Lineage for d4rn6a_ (4rn6 A:)
- Root: SCOPe 2.08
Class b: All beta proteins [48724] (180 folds) 
Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
barrel, closed; n=6, S=8; greek-key
duplication: consists of two domains of the same foldSuperfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) 
Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins) 
Protein Thrombin [50531] (2 species) Species Human (Homo sapiens) [TaxId:9606] [50532] (171 PDB entries)
Uniprot P00734 331-361,364-421 ! Uniprot P00734 334-360 364-510 518-619 ! Uniprot P00734 328-620 ! Uniprot P00734 355-621 ! Uniprot P00734 328-620
Domain d4rn6a_: 4rn6 A: [260812]
automated match to d3sqhe_
complexed with 15u; mutant
Details for d4rn6a_
PDB Entry: 4rn6 (more details), 3 Å
PDB Description: Structure of prethrombin-2 mutant s195a bound to the active site inhibitor argatroban
PDB Compounds: (A:) Thrombin heavy chainSCOPe Domain Sequences for d4rn6a_:
Sequence, based on SEQRES records: (download)
>d4rn6a_ b.47.1.2 (A:) Thrombin {Human (Homo sapiens) [TaxId: 9606]}
eadcglrplfekksledkterellesyidgrivegsdaeigmspwqvmlfrkspqellcg
aslisdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihpr
ynwrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwt
anvgkgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdaggpf
vmkspfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfge
Sequence, based on observed residues (ATOM records): (download)
>d4rn6a_ b.47.1.2 (A:) Thrombin {Human (Homo sapiens) [TaxId: 9606]}
eadcglrplfekksledkterellesyidgrivegsdaeigmspwqvmlfrkspqellcg
aslisdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihpr
ynwrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwt
apsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdaggpfvmkspf
nnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfge
SCOPe Domain Coordinates for d4rn6a_:
Click to download the PDB-style file with coordinates for d4rn6a_.
(The format of our PDB-style files is described here.)
(The format of our PDB-style files is described here.)
Timeline for d4rn6a_:
- d4rn6a_ first appeared in SCOPe 2.04
- d4rn6a_ appears in SCOPe 2.07
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