Lineage for d4i5la_ (4i5l A:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2009599Fold a.118: alpha-alpha superhelix [48370] (25 superfamilies)
    multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix
  4. 2009600Superfamily a.118.1: ARM repeat [48371] (26 families) (S)
  5. 2009754Family a.118.1.2: HEAT repeat [48385] (2 proteins)
    Pfam PF02985
    this is a repeat family; one repeat unit is 1b3u A:295-335 found in domain
  6. 2009755Protein Constant regulatory domain of protein phosphatase 2a, pr65alpha [48386] (2 species)
  7. 2009756Species Human (Homo sapiens) [TaxId:9606] [48387] (12 PDB entries)
  8. 2009757Domain d4i5la_: 4i5l A: [197094]
    Other proteins in same PDB: d4i5lc_, d4i5lf_
    automated match to d1b3ua_
    complexed with ca, mli, mn, peg

Details for d4i5la_

PDB Entry: 4i5l (more details), 2.43 Å

PDB Description: structural mechanism of trimeric pp2a holoenzyme involving pr70: insight for cdc6 dephosphorylation
PDB Compounds: (A:) Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

SCOPe Domain Sequences for d4i5la_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4i5la_ a.118.1.2 (A:) Constant regulatory domain of protein phosphatase 2a, pr65alpha {Human (Homo sapiens) [TaxId: 9606]}
mslypiavlidelrnedvqlrlnsikklstialalgvertrsellpfltdtiydedevll
alaeqlgtfttlvggpeyvhcllppleslatveetvvrdkaveslraishehspsdleah
fvplvkrlaggdwftsrtsacglfsvcyprvssavkaelrqyfrnlcsddtpmvrraaas
klgefakvleldnvkseiipmfsnlasdeqdsvrllaveacvniaqllpqedlealvmpt
lrqaaedkswrvrymvadkftelqkavgpeitktdlvpafqnlmkdceaevraaashkvk
efcenlsadcrenvimsqilpcikelvsdanqhvksalasvimglspilgkdntiehllp
lflaqlkdecpevrlniisnldcvnevigirqlsqsllpaivelaedakwrvrlaiieym
pllagqlgveffdeklnslcmawlvdhvyaireaatsnlkklvekfgkewahatiipkvl
amsgdpnylhrmttlfcinvlsevcgqdittkhmlptvlrmagdpvanvrfnvakslqki
gpildnstlqsevkpilekltqdqdvdvkyfaqealtvlsla

SCOPe Domain Coordinates for d4i5la_:

Click to download the PDB-style file with coordinates for d4i5la_.
(The format of our PDB-style files is described here.)

Timeline for d4i5la_: