Lineage for d4geea_ (4gee A:)

  1. Root: SCOPe 2.03
  2. 1396887Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1429695Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
    8-stranded mixed beta-sheet; 2 layers: alpha/beta
  4. 1429696Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (5 families) (S)
  5. 1430131Family d.122.1.0: automated matches [227160] (1 protein)
    not a true family
  6. 1430132Protein automated matches [226867] (10 species)
    not a true protein
  7. 1430133Species Enterococcus faecalis [TaxId:226185] [226590] (9 PDB entries)
  8. 1430137Domain d4geea_: 4gee A: [221875]
    automated match to d1kzna_
    protein/DNA complex; complexed with 0wt, gol

Details for d4geea_

PDB Entry: 4gee (more details), 1.7 Å

PDB Description: Pyrrolopyrimidine inhibitors of DNA gyrase B and topoisomerase IV, part I: structure guided discovery and optimization of dual targeting agents with potent, broad-spectrum enzymatic activity.
PDB Compounds: (A:) DNA gyrase subunit b

SCOPe Domain Sequences for d4geea_:

Sequence, based on SEQRES records: (download)

>d4geea_ d.122.1.0 (A:) automated matches {Enterococcus faecalis [TaxId: 226185]}
gleavrkrpgmyigstsgeglhhlvweivdnsidealagfaksiqviiepddsitviddg
rgipvgiqaktgrpavetvftvlhaggkfggggykvsgglhgvgssvvnalstsldvrvy
kdgkvyyqeyrrgavvddlkvieetdrhgttvhfipdpeiftettvydfdklatrvrela
flnrglhisiedrregqedkkeyhyegleh

Sequence, based on observed residues (ATOM records): (download)

>d4geea_ d.122.1.0 (A:) automated matches {Enterococcus faecalis [TaxId: 226185]}
gleavrkrpgmyigstsgeglhhlvweivdnsidealagfaksiqviiepddsitviddg
rgipvgiqaktgrpavetvftvlhgvgssvvnalstsldvrvykdgkvyyqeyrrgavvd
dlkvieetdrhgttvhfipdpeiftettvydfdklatrvrelaflnrglhisiedrregq
edkkeyhyegleh

SCOPe Domain Coordinates for d4geea_:

Click to download the PDB-style file with coordinates for d4geea_.
(The format of our PDB-style files is described here.)

Timeline for d4geea_: