Lineage for d4fk6a_ (4fk6 A:)

  1. Root: SCOPe 2.08
  2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. Protein automated matches [190417] (36 species)
    not a true protein
  7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1454 PDB entries)
  8. Domain d4fk6a_: 4fk6 A: [221242]
    automated match to d3bhhd_
    complexed with 0uj

Details for d4fk6a_

PDB Entry: 4fk6 (more details), 2.2 Å

PDB Description: JAK1 kinase (JH1 domain) in complex with compound 72
PDB Compounds: (A:) Tyrosine-protein kinase JAK1

SCOPe Domain Sequences for d4fk6a_:

Sequence, based on SEQRES records: (download)

>d4fk6a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tevdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslkpesggnhiadl
kkeieilrnlyhenivkykgictedggngiklimeflpsgslkeylpknknkinlkqqlk
yavqickgmdylgsrqyvhrdlaarnvlvesehqvkigdfgltkaietdkeyytvkddrd
spvfwyapeclmqskfyiasdvwsfgvtlhelltycdsdsspmalflkmigpthgqmtvt
rlvntlkegkrlpcppncpdevyqlmrkcwefqpsnrtsfqnliegfeallk

Sequence, based on observed residues (ATOM records): (download)

>d4fk6a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tevdpthfekrflkrirdlgefgkvelcrydpegdntgeqvavkslkpenhiadlkkeie
ilrnlyhenivkykgictedggngiklimeflpsgslkeylpknknkinlkqqlkyavqi
ckgmdylgsrqyvhrdlaarnvlvesehqvkigdfgltkaietdkeyytvkddrdspvfw
yapeclmqskfyiasdvwsfgvtlhelltycdsdsspmalflkmigpthgqmtvtrlvnt
lkegkrlpcppncpdevyqlmrkcwefqpsnrtsfqnliegfeallk

SCOPe Domain Coordinates for d4fk6a_ are not available.

Timeline for d4fk6a_:

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Domains from other chains:
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d4fk6b_