Lineage for d4c8da_ (4c8d A:)

  1. Root: SCOPe 2.08
  2. Class b: All beta proteins [48724] (180 folds)
  3. Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
    one turn of helix is made by two pairs of antiparallel strands linked with short turns
    has appearance of a sandwich of distinct architecture and jelly-roll topology
  4. Superfamily b.82.2: Clavaminate synthase-like [51197] (16 families) (S)
    Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold
  5. Family b.82.2.14: Jumonji domain / Histone demethylase core [254153] (7 proteins)
    Jumonji domain; Pfam PF02375 (JmjN) and Pfam PF02373 (JmjC); relationship to FIH1 (b.82.2.6) described in PubMed 16983801
    Pfam PF02375 (JmjN) and Pfam PF02373 (JmjC); relationship to FIH1 (b.82.2.6) described in PubMed 16983801; some members include C-terminal helical subdomain (Pfam PF17811)
  6. Protein JHDM2B core [254344] (1 species)
  7. Species Human (Homo sapiens) [TaxId:9606] [254777] (1 PDB entry)
  8. Domain d4c8da_: 4c8d A: [251347]
    complexed with act, cl, gol, mn, oga

Details for d4c8da_

PDB Entry: 4c8d (more details), 2.18 Å

PDB Description: crystal structure of jmjc domain of human histone 3 lysine-specific demethylase 3b (kdm3b)
PDB Compounds: (A:) lysine-specific demethylase 3b

SCOPe Domain Sequences for d4c8da_:

Sequence, based on SEQRES records: (download)

>d4c8da_ b.82.2.14 (A:) JHDM2B core {Human (Homo sapiens) [TaxId: 9606]}
tshswlcdgrllclhdpsnknnwkifrecwkqgqpvlvsgvhkklkselwkpeafsqefg
dqdvdlvncrncaiisdvkvrdfwdgfeiickrlrsedgqpmvlklkdwppgedfrdmmp
trfedlmenlplpeytkrdgrlnlasrlpsyfvrpdlgpkmynayglitaedrrvgttnl
hldvsdavnvmvyvgipigegahdeevlktidegdadevtkqrihdgkekpgalwhiyaa
kdaekirellrkvgeeqgqenppdhdpihdqswyldqtlrkrlyeeygvqgwaivqflgd
avfipagaphqvhnlyscikvaedfvspehvkhcfrltqef

Sequence, based on observed residues (ATOM records): (download)

>d4c8da_ b.82.2.14 (A:) JHDM2B core {Human (Homo sapiens) [TaxId: 9606]}
tshswlcdgrllclhdpsnknnwkifrecwkqgqpvlvsgvhkklkselwkpeafsqefg
dqdvdlvncrncaiisdvkvrdfwdgfeiickrlrsedgqpmvlklkdwppgedfrdmmp
trfedlmenlplpeytkrdgrlnlasrlpsyfpkmynayglitaedrrvgttnlhldvsd
avnvmvyvgipigegahdeevlktidegdadevtkqrihdgkekpgalwhiyaakdaeki
rellrkvgeeqgqpdhdpihdqswyldqtlrkrlyeeygvqgwaivqflgdavfipagap
hqvhnlyscikvaedfvspehvkhcfrltqef

SCOPe Domain Coordinates for d4c8da_ are not available.

Timeline for d4c8da_: