Lineage for d4c2ab_ (4c2a B:)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2851636Fold c.10: Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) [52046] (3 superfamilies)
    2 curved layers, a/b; parallel beta-sheet; order 1234...N; there are sequence similarities between different superfamilies
  4. 2851705Superfamily c.10.2: L domain-like [52058] (9 families) (S)
    less regular structure consisting of variable repeats
  5. 2851868Family c.10.2.7: Ngr ectodomain-like [75142] (7 proteins)
    applies to all domains of a family if the common domain is composed of a different number of small repeating units
    this is a repeat family; one repeat unit is 1xwd C:97-122 found in domain
  6. 2851908Protein automated matches [235852] (2 species)
    not a true protein
  7. 2851909Species Human (Homo sapiens) [TaxId:9606] [235853] (2 PDB entries)
  8. 2851910Domain d4c2ab_: 4c2a B: [235854]
    Other proteins in same PDB: d4c2aa_
    automated match to d1p8va_
    complexed with act, ca, cac, peg; mutant

Details for d4c2ab_

PDB Entry: 4c2a (more details), 2.08 Å

PDB Description: crystal structure of high-affinity von willebrand factor a1 domain with r1306q and i1309v mutations in complex with high affinity gpib alpha
PDB Compounds: (B:) platelet glycoprotein ib alpha chain

SCOPe Domain Sequences for d4c2ab_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4c2ab_ c.10.2.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
hpicevskvashlevncdkrrltalppdlpkdttilhlsenllytfslatlmpytrltql
nldrceltklqvdgtlpvlgtldlshnqlqslpllgqtlpaltvldvsfnrltslplgal
rglgelqelylkgnelktlppglltptpkleklslannrltelpagllnglenldtlllq
enslytipkgffgshllpfaflhgnpwlcnceilyfrrwlqdnaenvyvwkqvvdvkavt
snvasvqcdnsdkfpvykypgkgcpt

SCOPe Domain Coordinates for d4c2ab_:

Click to download the PDB-style file with coordinates for d4c2ab_.
(The format of our PDB-style files is described here.)

Timeline for d4c2ab_: