Lineage for d3zcmb_ (3zcm B:)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2883383Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
    3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest
  4. 2885833Superfamily c.55.3: Ribonuclease H-like [53098] (18 families) (S)
    consists of one domain of this fold
  5. 2886113Family c.55.3.2: Retroviral integrase, catalytic domain [53107] (2 proteins)
    Pfam PF00665
  6. 2886283Protein automated matches [190209] (5 species)
    not a true protein
  7. 2886418Species Human immunodeficiency virus [TaxId:12721] [193331] (20 PDB entries)
  8. 2886432Domain d3zcmb_: 3zcm B: [193332]
    automated match to d1bizb_
    complexed with act, gol, px3, so4

Details for d3zcmb_

PDB Entry: 3zcm (more details), 1.8 Å

PDB Description: Small molecule inhibitors of the LEDGF site of HIV integrase identified by fragment screening and structure based design.
PDB Compounds: (B:) hiv integrase

SCOPe Domain Sequences for d3zcmb_:

Sequence, based on SEQRES records: (download)

>d3zcmb_ c.55.3.2 (B:) automated matches {Human immunodeficiency virus [TaxId: 12721]}
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtd
ngsnftsttvkaacwwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlktav
qmavfihnhkrkggiggysagerivdiiatdiq

Sequence, based on observed residues (ATOM records): (download)

>d3zcmb_ c.55.3.2 (B:) automated matches {Human immunodeficiency virus [TaxId: 12721]}
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtd
ngsnftsttvkaacwwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlktav
qmavfihnhkrkgysagerivdiiatdiq

SCOPe Domain Coordinates for d3zcmb_:

Click to download the PDB-style file with coordinates for d3zcmb_.
(The format of our PDB-style files is described here.)

Timeline for d3zcmb_: